Optimized CRISPR-CAS double nickase systems, methods and compositions for sequence manipulation
US-12553065-B2 · Feb 17, 2026 · US
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Lin Chie-Yu patents
Lin Chie-Yu is listed as an inventor on 23 patents in our database. Major assignees and classification codes are summarized below.
| Metric | Value |
|---|---|
| Inventor | Lin Chie-Yu |
| Total patents | 23 |
| First publication | Jun 2, 2016 |
| Latest publication | Feb 17, 2026 |
Notable patents
Publications ranked by popularity score, then publication date.
Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders
US-12410435-B2 · Sep 9, 2025 · US
Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems
US-12258595-B2 · Mar 25, 2025 · US
Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems
US-2024035007-A1 · Feb 1, 2024 · US
Optimized crispr-cas double nickase systems, methods and compositions for sequence manipulation
US-2023374550-A1 · Nov 23, 2023 · US
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
US-2023365950-A1 · Nov 16, 2023 · US
Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems
US-11597919-B2 · Mar 7, 2023 · US
Optimized CRISPR-Cas double nickase systems, methods and compositions for sequence manipulation
US-11597949-B2 · Mar 7, 2023 · US
Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders
US-11591581-B2 · Feb 28, 2023 · US
Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
US-2021292794-A1 · Sep 23, 2021 · US
Recent patents
Latest publications not already listed above.
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
US-2021277370-A1 · Sep 9, 2021 · US
Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
US-11008588-B2 · May 18, 2021 · US
Optimized crispr-cas double nickase systems, methods and compositions for sequence manipulation
US-2020377912-A1 · Dec 3, 2020 · US
Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders
US-10851357-B2 · Dec 1, 2020 · US
Optimized CRISPR-Cas double nickase systems, methods and compositions for sequence manipulation
US-10711285-B2 · Jul 14, 2020 · US
Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems
US-2020115687-A1 · Apr 16, 2020 · US
Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems
US-10550372-B2 · Feb 4, 2020 · US
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
US-2019153412-A1 · May 23, 2019 · US
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
US-2016355796-A1 · Dec 8, 2016 · US
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
US-2016354487-A1 · Dec 8, 2016 · US
Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems
US-2016355797-A1 · Dec 8, 2016 · US
Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
US-2016186213-A1 · Jun 30, 2016 · US
Optimized crispr-cas double nickase systems, methods and compositions for sequence manipulation
US-2016153006-A1 · Jun 2, 2016 · US
Major assignees
Companies most often associated with this inventor's publications.
| Assignee | Patents |
|---|---|
| Broad Inst Inc | 23 |
| Massachusetts Inst Technology | 23 |
| Harvard College | 15 |
| Univ Iowa Res Found | 8 |
| Univ Tokyo | 6 |
Top CPC classifications
Most common classification codes across this inventor's patents.
| CPC | Patents |
|---|---|
| C12N15/907 | 23 |
| C12N9/22 | 23 |
| C12N15/113 | 20 |
| A61K48/005 | 20 |
| C12N15/102 | 17 |