Modulators of methyl modifying enzymes, compositions and uses thereof

Patent metadata

Field	Value
Publication number	US-RE47428-E
Application number	US-201815878663-A
Country	US
Kind code	E1
Filing date	Jan 24, 2018
Priority date	Feb 10, 2012
Publication date	Jun 11, 2019
Grant date	Jun 11, 2019

Abstract

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

First claim

The invention claimed is:

1. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

2. The compound of claim 1 , wherein the compound is of the formula:

or a pharmaceutically acceptable salt thereof.

3. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier.

4. The pharmaceutical composition of claim 3 , wherein the compound is of the formula:

or a pharmaceutically acceptable salt thereof.

Assignees

• Constellation Pharmaceuticals Inc

Inventors

• Albrecht Brian K
• Audia James Edmund
• Dakin Les A
• Gehling Victor S
• Harmange Jean-Christophe
• Nasveschuk Christopher G
• Vaswani Rishi G

Classifications

• A61P35/00

  Antineoplastic agents · CPC title

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P13/10

  of the bladder · CPC title

• A61P13/12

  of the kidneys · CPC title

• A61P11/00

  Drugs for disorders of the respiratory system · CPC title