Retrieval of similar patient cases based on disease probability vectors

Patent metadata

Field	Value
Publication number	US-9997260-B2
Application number	US-81002108-A
Country	US
Kind code	B2
Filing date	Dec 8, 2008
Priority date	Dec 28, 2007
Publication date	Jun 12, 2018
Grant date	Jun 12, 2018

Abstract

A method of retrieving similar patient cases from a medical database includes matching a current patient case against a plurality of clinical profiles resulting in a set of matching clinical profiles. The method further includes determining a degree of membership of the current patient case in each clinical profile from the set of matching clinical profiles based upon a degree of match between the current patient case and the clinical profile. For at least one clinical profile from the set of matching clinical profiles, the method includes retrieving those similar patient cases from the medical database that have a substantially corresponding degree of membership as the current patient case.

First claim

The invention claimed is:

1. A method of retrieving similar patient cases from a medical database, the method comprising:
storing, by the medical database, a plurality of clinical profiles, each clinical profile defined by a different medical condition and including a plurality of specifications associated with the medical condition, wherein each specification is associated with a weight, the weight indicating an importance of the specification to a diagnosis of the medical condition, wherein each clinical profile is divided into a plurality of levels with a set of the specifications within each level, wherein the specifications include comorbidities;
storing, by the medical database, a plurality of patient cases comprising patient data, the patient data corresponding to one or more specifications;
defining for each clinical profile, by a processor, membership rules defining degrees of membership in the clinical profile, wherein membership in the clinical profile is determined by a cumulative presence of one or more weighted specifications comprised in the clinical profile;
indexing, by the processor, each patient case in the medical database as having a degree of membership in one or more clinical profiles based on the membership rules;
receiving, by the processor, a current patient case comprising current patient data;
searching, by the processor, the medical database comprising the plurality of clinical profiles and the plurality of patient cases;
matching, by the processor, the current patient case against the plurality of clinical profiles resulting in a set of matching clinical profiles, wherein the matching includes comparing the patient data for the current patient case with the specifications to determine whether there is a match for any of the specifications;
determining, by the processor, for each clinical profile from the set of matching clinical profiles, the degree of membership of the current patient case based upon the membership rules; and
retrieving, by the processor, based on the clinical profiles in the set of matching clinical profiles, similar patient cases from the medical database that are identified as having a substantially corresponding degree of membership in at least one of the clinical profiles as the current patient case.

2. The method according to claim 1 , wherein the matching comprises:
matching the current patient case at multiple points in time against the plurality of clinical profiles resulting in a set of matching clinical profiles for each of the multiple points in time;
and performing the step of determining and retrieving for each of the multiple points in time.

3. The method of claim 1 , wherein the retrieving includes retrieving patient cases that are identified as having a substantially corresponding degree of membership in each of the clinical profiles of a membership set of the matching clinical profiles as the current patient case.

4. The method according to claim 1 , wherein each of the clinical profiles catalogs a medical condition according to at least one of the following patient data variables: conditional data, event-specific data, demographic data, clinical data, medical history, family history, social history, diagnosis history, and treatment history.

5. The method according to claim 1 , wherein the current patient case matches the clinical profile if all the specifications of at least a definitional one of the levels are matched with the patient data.

6. The method according to claim 1 , wherein each of the levels is associated with a weight and wherein the degree of membership is based on at least one matching specification and its associated weight.

7. The method according to claim 1 , wherein the degree of membership for a clinical profile is based on a number of the specifications that match the patient data.

8. The method of claim 1 , further comprising, identifying a test to be performed on the patient whose outcome is one of the specifications of a clinical profile which has at least one other specification which matches the patient data.

9. The method according to claim 1 , further comprising retrieving information about treatment given a patient in at least one of the similar patient cases from the medical database and presenting the information to a user.

10. The method of claim 1 , further comprising, for one of the retrieved similar patient cases from the medical database, identifying for a user the clinical profile which was used to retrieve the similar patient case.

11. The method of claim 1 , further comprising linking the current patient case to at least one clinical profile from the set of matching profiles.

12. The method of claim 11 , further comprising linking the current patient case to a membership set of the set of matching profiles based on the degree of membership.

13. The method of claim 11 , further comprising time stamping the current patient case based on a time at which the current patient case is linked to the at least one clinical profile from the set of matching profiles.

14. A system for retrieving similar patient cases from a medical database, the system comprising a memory storing a set of instruction and a processor, wherein the processor executes the set of instructions to implement:
a searcher which searches the medical database comprising a plurality of clinical profiles and a plurality of patient cases,
wherein each clinical profile is defined by a different medical condition and includes a plurality of specifications associated with the medical condition, wherein each specification is associated with a weight, the weight indicating an importance of the specification to a diagnosis of the medical condition, wherein each clinical profile is divided into a plurality of levels with a set of the specifications within each level, wherein the specifications include comorbidities,
wherein each patient case comprises patient data, the patient data corresponding to one or more specifications,
wherein each clinical profile defines membership rules, the membership rules defining degrees of membership in the clinical profile, wherein membership in the clinical profile is determined by a cumulative presence of one or more weighted specifications comprised in the clinical profile,
wherein each patient case is indexed in the database as having a degree of membership in one or more clinical profiles based on the membership rules;

a matcher which matches a current patient case comprising current patient data against the plurality of clinical profiles resulting in a set of matching clinical profiles, wherein the matcher compares the patient data for the current patient case with the specifications to determine whether there is a match for any of the specifications;
a determiner which determines the degree of membership of the current patient case in each clinical profile from the set of matching clinical profiles based upon the membership rules;
and a retriever which, based on the clinical profiles in the set of matching clinical profiles, retrieves similar patient cases from the medical database that are identified as having a substantially corresponding degree of membership in at least one of the matching clinical profiles as the current patient case.

15. The system according to claim 14 , wherein the matcher is designed for matching the current patient case at multiple points in time against the plurality of clinical profiles resulting in a set of matching clinical profiles for each of the multiple points in time;
and the determiner and retriever are designed for determining and retrieving for each of the multiple points in

Assignees

• Dutta Pradyumna
• Ennett Colleen M
• Koninklijke Philips Nv

Inventors

• Dutta Pradyumna
• Ennett Colleen M

Classifications

• G16H50/70 Primary

  for mining of medical data, e.g. analysing previous cases of other patients · CPC title