Quenched dendrimeric dyes for florescence detection
US-9249306-B2 · Feb 2, 2016 · US
Targeted probes of cellular physiology
US9995679B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9995679-B2 |
| Application number | US-201113696877-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 25, 2011 |
| Priority date | May 25, 2010 |
| Publication date | Jun 12, 2018 |
| Grant date | Jun 12, 2018 |
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Abstract
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Biosensor comprising an activatable acceptor fluorogen linked via a linker to a donor which transfers energy to the fluorogen on detecting an analyte wherein the fluorogen component reacts and a 100 fold increase in intensity results when the fluorogen interacts non-covalently with an activator e.g. fluorogen activator peptide.
First claim
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We claim: 1. A complex comprising: a biosensor comprising malachite green covalently linked by a linker to a single ion-sensitive cyanine dye or an ion-sensitive rhodamine dye that interacts with an analyte ion; and an activator of malachite green bound to the malachite green, wherein the activator comprises one of SEQ ID NOS: 3-9, wherein the malachite green produces a fluorescence signal increase of at least 100-fold when it is bound to the activator as compared to when no a…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- G01N21/64Primary
Physics · mapped topic
- G01N33/533Primary
Physics · mapped topic
Physics · mapped topic
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- What does patent US9995679B2 cover?
- Biosensor comprising an activatable acceptor fluorogen linked via a linker to a donor which transfers energy to the fluorogen on detecting an analyte wherein the fluorogen component reacts and a 100 fold increase in intensity results when the fluorogen interacts non-covalently with an activator e.g. fluorogen activator peptide.
- Who is the assignee on this patent?
- Waggoner Alan, Bruchez Marcel P, Schmidt Brigitte F, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification G01N21/64. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Jun 12 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).