Pain-relieving compositions and uses therefor

US9994534B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9994534-B2
Application numberUS-201715669834-A
CountryUS
Kind codeB2
Filing dateAug 4, 2017
Priority dateDec 29, 2006
Publication dateJun 12, 2018
Grant dateJun 12, 2018

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Compositions and methods are for inducing, promoting or otherwise facilitating pain relief. More particularly, sub-normovasodilatory doses of nitric oxide donors are used in the therapeutic management of vertebrate animals including humans, for the prevention or alleviation of pain, especially neuropathic pain. In some applications of the method, nitric oxide donors can be administered by any suitable route so as to provide concentrations of NO that are about ½ to 10 −15 times those known to induce vasodilation in normal circulations.

First claim

Opening claim text (preview).

What is claimed is: 1. A compound of formula (I): wherein one of R 1 and R 2 is selected from C 1-3 alkyl; and the other of R 1 and R 2 is selected from C 1 alkylphenyl substituted with hydroxyl; ethyl substituted with hydroxyl; and —CH 2 N(ethyl) 2 . 2. The compound according to claim 1 wherein one of R 1 and R 2 is methyl. 3. The compound according to claim 1 wherein one of R 1 and R 2 is methyl and the other is C 1 alkylphenyl substituted with hydroxyl. 4. The compound according to claim 3 wherein the hydroxyl is substituted on the alkyl group. 5. The compound according to claim 1 wherein one of R 1 and R 2 is methyl and the other is ethyl substituted with hydroxyl. 6. The compound according to claim 1 wherein one of R 1 and R 2 is methyl and the other is —CH 2 N(ethyl) 2 .

Assignees

Inventors

Classifications

  • Medicinal preparations containing organic active ingredients · CPC title

  • Oxadiazoles · CPC title

  • C07D271/08Primary

    1,2,5-Oxadiazoles; Hydrogenated 1,2,5-oxadiazoles · CPC title

  • Esters, e.g. nitroglycerine, selenocyanates · CPC title

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What does patent US9994534B2 cover?
Compositions and methods are for inducing, promoting or otherwise facilitating pain relief. More particularly, sub-normovasodilatory doses of nitric oxide donors are used in the therapeutic management of vertebrate animals including humans, for the prevention or alleviation of pain, especially neuropathic pain. In some applications of the method, nitric oxide donors can be administered by any s…
Who is the assignee on this patent?
Univ Queensland
What technology area does this patent fall under?
Primary CPC classification C07D271/08. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jun 12 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).