System and method for limited flow respiratory therapy

Patent metadata

Field	Value
Publication number	US-9987444-B2
Application number	US-201214127523-A
Country	US
Kind code	B2
Filing date	Jul 31, 2012
Priority date	Jul 1, 2011
Publication date	Jun 5, 2018
Grant date	Jun 5, 2018

Abstract

Methods and system of respiratory therapy treat sleep apnea by particular elevated pressure levels during the end of exhalation phases. Inhalation pressure levels may thus be significantly reduced and be, on average, lower than the exhalation pressure levels.

First claim

The invention claimed is:

1. A system for treating sleep disordered breathing of a subject having an airway, the system comprising:
a pressure generator configured to generate a pressurized flow of breathable gas for delivery to the airway of the subject via one or more gas delivery components; and
one or more processors configured to execute computer program modules, the computer program modules comprising:
a timing module configured to determine transitional moments that separate inhalation phases from exhalation phases and/or vice versa; and
a control module configured to control the pressure generator to adjust pressure levels of the pressurized flow of breathable gas, wherein the control module is configured to control the pressure generator to provide the pressurized flow of breathable gas at inhalation pressure levels during inhalation phases, and to provide the pressurized flow of breathable gas at exhalation pressure levels during exhalation phases, wherein:
an average of the exhalation pressure levels of the pressurized flow of breathable gas provided to the subject from the pressure generator is higher than a prescribed constant positive airway pressure therapy pressure level, and
an average of the inhalation pressure levels of the pressurized flow of breathable gas provided to the subject from the pressure generator is lower than the prescribed constant positive airway pressure therapy pressure level.

2. The system of claim 1 , wherein the control module is further configured such that a given exhalation pressure level for a given exhalation phase steadily increases in a ramped manner throughout at least the first 10% of the given exhalation phase.

3. The system of claim 1 , wherein the control module is further configured such that the pressure levels of the pressurized flow of breathable gas increase from the lowest inhalation pressure level during a given inhalation phase to the highest exhalation pressure level during a subsequent exhalation phase that immediately follows the given inhalation phase in a ramped manner over a ramping period spanning at least 50% of a combined duration of the given inhalation phase and the subsequent exhalation phase.

4. The system of claim 1 , wherein the control module is further configured such that: (1) a given inhalation pressure level is 0 cmH2O or less, and (2) a given exhalation pressure level is substantially constant throughout a predetermined period within a given exhalation phase, wherein the predetermined period comprises about a final 10% of the given exhalation phase, and wherein the given exhalation pressure level is elevated from the reference sleep disorder breathing constant positive airway pressure therapy pressure levels by at least 0.5 cmH2O.

5. The system of claim 1 , wherein the prescribed constant positive airway pressure therapy pressure level is 10 cmH 2 O and wherein the average of the exhalation pressure levels is higher than the prescribed constant positive airway pressure therapy pressure level by approximately 2 cmH 2 O.

6. The system of claim 1 , wherein the control module is configured such that the average of the exhalation pressure levels is higher than the prescribed constant positive airway pressure therapy pressure level by a first treatment amount of pressure, and responsive to detection of an occurrence of a respiratory event in the subject, the average of the exhalation pressure levels is higher than the prescribed constant positive airway pressure therapy pressure level by a second increased treatment amount of pressure relative to the first treatment amount of pressure.

7. The system of claim 1 , further comprising:
a subject interface configured to place the pressure generator in fluid communication with the subject, wherein the subject interface includes a flow resistor,
wherein the control module is configured to control the pressure generator to adjust pressure levels of the pressurized flow of breathable gas such that resistance of the flow resistor and resistance of the one or more gas delivery components are both taken into account to prevent occurrence of a pressure peak during a first portion of a given exhalation phase relative to exhalation pressures during a second portion of the given exhalation phase.

8. The system of claim 7 , wherein the one or more gas delivery components include a 6 mm-9 mm diameter limited flow hose having a greater resistance to gas flow than a 22 mm diameter size hose.

9. A system configured to treat sleep disorder breathing of a subject having an airway, the system comprising:
means for generating a pressurized flow of breathable gas for delivery to the airway of the subject;
means for delivering breathable gas to the airway of the subject;
means for determining transitional moments that separate inhalation phases from exhalation phases and/or vice versa; and
means for adjusting pressure levels of the pressurized flow, such that inhalation pressure levels are provided during inhalation phases and exhalation pressure levels are provided during exhalation phases, wherein:
an average of the exhalation pressure levels of the pressurized flow of breathable gas provided to the subject from the means for generating the pressurized flow of breathable gas is higher than a prescribed constant positive airway pressure therapy pressure level, and
an average of the inhalation pressure levels of the pressurized flow of breathable gas provided to the subject from the means for generating the pressurized flow of breathable gas is lower than the prescribed constant positive airway pressure therapy pressure level.

10. The system of claim 9 , wherein operation of the means for adjusting pressure levels of the pressurized flow includes steadily increasing a given exhalation pressure level in a ramped manner for a given exhalation phase throughout at least the first 10% of the given exhalation phase.

11. The system of claim 9 , further comprising:
means for placing the means for generating a pressurized flow of breathable gas in fluid communication with the subject, including a means for increasing flow resistance;
wherein the means for adjusting pressure levels of the pressurized flow takes into account both a resistance of the means for increasing flow resistance and a resistance of the means for delivering breathable gas to the airway of the subject to prevent occurrence of a pressure peak during a first portion of a given exhalation phase relative to exhalation pressures during a second portion of the given exhalation phase.

12. The system of claim 9 , wherein operation of the means for adjusting pressure levels of the pressurized flow includes increasing a pressure level of the pressurized flow of breathable gas from the lowest inhalation pressure level during a given inhalation phase to the highest exhalation pressure level during a subsequent exhalation phase that immediately follows the given inhalation phase in a ramped manner such that the pressure level increases over a ramping period spanning at least 50% of a combined duration of the given inhalation phase and the subsequent exhalation phase.

13. The system of claim 9 , wherein operation of the means for adjusting pressure levels of the pressurized flow includes: (1) controlling a given inhalation pressure during a given inhalation phase such that the given inhalation pressure is 0 cmH2O or less, and (2) controlling a given exhalation pressure during a given exhalation phase such that the given exhalation pressure is substantially constant throughout a predetermined period within the given exhalation phase, wherein the predetermined period comprises about a final 10% of the given

Assignees

• Colbaugh Michael Edward
• Koninklijke Philips Nv

Inventors

• Colbaugh Michael Edward

Classifications

• A61M16/0057

  Pumps therefor · CPC title

• A61M16/0051 Primary

  with alarm devices · CPC title

• A61M2205/505

  Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches · CPC title

• A61M2205/3368

  Temperature · CPC title

• A61M16/0666

  Nasal cannulas or tubing (devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02) · CPC title