Closed system transfer device
US-2024216222-A1 · Jul 4, 2024 · US
US9987194B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9987194-B2 |
| Application number | US-201514835757-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 26, 2015 |
| Priority date | Aug 26, 2014 |
| Publication date | Jun 5, 2018 |
| Grant date | Jun 5, 2018 |
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Described in one aspect is a multi-cell or multi-chambered container for sealing various materials such as therapeutic or diagnostic agents, animal or human tissue, tissue samples, specimens, blood, genetic material, or any other material. The container includes seals formed by folding the wall of the elongate body transverse to the interior of the elongate body and maintaining the folded wall portions adjacent one another or joining them together. In another aspect, the container disclosed may be made according to a method involving creating multiple seals at various locations along the elongate body thus creating sealed voids or cells between the seals within the elongate body.
Opening claim text (preview).
What is claimed is: 1. A container, comprising: an elongate body with a first, second, and third seal at three separate locations respectively along the elongate body defining a first hermetically sealed void within the elongate body between the first and second seals, and a second hermetically sealed void within the elongate body between the second and third seals; wherein at least one of the first or second hermetically sealed voids contains a therapeutic or diagnostic agent; wherein the elongate body has a wall defining an interior lumen that has an inner surface; wherein the first seal includes a plurality of folds in the wall defining corresponding sealing portions of the wall; wherein the sealing portions extend transverse to the interior lumen; and wherein the sealing portions are joined to one another to form the first seal, and wherein the first seal, the second seal, and/or the third seal each includes at least three folds defining at least three sealing portions per seal, the sealing portions extending transverse to the interior lumen in different directions, and wherein the sealing portions are on the inner surface of the interior lumen. 2. The container of claim 1 , wherein an interior width of the interior lumen at a location adjacent the first, second, or third seal is narrower than the interior width at a location other than adjacent the first, second, and third seal locations. 3. The container of claim 1 , wherein the wall of the elongate member includes a thermoplastic polymeric material. 4. The container of claim 1 , further comprising: a fourth seal at a fourth separate locations along the elongate body defining a third hermetically sealed void within the elongate body between the third and fourth seals; wherein the second hermetically sealed void contains a therapeutic or diagnostic agent; wherein the first and third hermetically sealed voids do not contain a therapeutic or diagnostic agent; and wherein the fourth seal includes at least three folds in the wall defining at least three sealing portions extending transverse to the interior lumen in different directions, and wherein the at least three sealing portions of the fourth seal are fused together to form a unitary structure. 5. The container of claim 1 , wherein the therapeutic or diagnostic agent includes cells. 6. The container of claim 3 , wherein the thermoplastic polymeric material is Ethylene-Vinyl Acetate (EVA). 7. The container of claim 1 , wherein the sealing portions of the wall are contiguous with the wall. 8. A container, comprising: an elongate body with a first, second, and third seal at three separate locations respectively along the elongate body defining a first hermetically sealed void within the elongate body between the first and second seals, and a second hermetically sealed void within the elongate body between the second and third seals; wherein the first hermetically sealed void maintains a sterile puncture site through the second seal into the second hermetically sealed void; wherein the second hermetically sealed void contains a biological material comprising cells; wherein the elongate body has a wall defining an interior lumen that has an inner surface; wherein the first seal includes a plurality of folds in the wall defining corresponding sealing portions of the wall; wherein the sealing portions extend transverse to the interior lumen; wherein the sealing portions are joined to one another to form the first seal; and a fourth seal at a fourth separate location along the elongate body defining a third hermetically sealed void within the elongate body between the third and fourth seals; wherein the third hermetically sealed void maintains a sterile puncture site through the third seal into the second hermetically sealed void and does not contain a therapeutic or diagnostic agent; and wherein the fourth seal includes at least three folds in the wall defining at least three sealing portions extending transverse to the interior lumen in different directions, and wherein the at least three sealing portions of the fourth seal are fused together to form a unitary structure. 9. The container of claim 8 , wherein the wall of the elongate member includes a thermoplastic polymeric material. 10. The container of claim 8 , wherein the sealing portions of the wall are contiguous with the wall.
Use of {PU, i.e.} polyureas or polyurethanes {or derivatives thereof}, as moulding material · CPC title
Septums, pierceable membranes · CPC title
Stretching or tensioning the joint area during joining · CPC title
Closing the ends of tubular or hollow single articles, e.g. closing the ends of bags (closing tube ends B29C57/10) · CPC title
Containers having several compartments for products to be mixed · CPC title
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