Process for the preparation of 4-amino-5-fluoro-3-chloro-6-(substituted)picolinates
US-9212141-B2 · Dec 15, 2015 · US
US9981911B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9981911-B2 |
| Application number | US-201715683813-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 23, 2017 |
| Priority date | Dec 13, 2012 |
| Publication date | May 29, 2018 |
| Grant date | May 29, 2018 |
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4-Amino-5-fluoro-3-chloro-6-(substituted)picolinates are prepared from trifluoroacetic acid, p-methoxyaniline, a 3,3-dialkoxyprop-1-yne and a substituted methylene amine by a series of steps.
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What is claimed is: 1. A compound of Formula E wherein R 1 represents C 1 -C 4 alkyl, cyclopropyl, C 2 -C 4 alkenyl or phenyl substituted with from 1 to 4 substituents independently selected from halogen, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy or C 1 -C 4 haloalkoxy, and R 3 represents C 1 -C 4 alkyl. 2. A compound of Formula G wherein R 1 represents C 1 -C 4 alkyl, cyclopropyl, C 2 -C 4 alkenyl or phenyl substituted with from 1 to 4 substituents independently selected from halogen, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy or C 1 -C 4 haloalkoxy, and R 3 represents C 1 -C 4 alkyl. 3. A compound of Formula H wherein R 1 represents C 1 -C 4 alkyl, cyclopropyl, C 2 -C 4 alkenyl or phenyl substituted with from 1 to 4 substituents independently selected from halogen, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy or C 1 -C 4 haloalkoxy.
Nitrogen atoms (nitro radicals C07D213/61) · CPC title
being acyclic · CPC title
Processes of preparation · CPC title
Unsubstituted amino or imino radicals · CPC title
Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals · CPC title
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