Dual-Action Compounds Targeting Adenosine A2A Receptor and Adenosine Transporter for Prevention and Treatment of Neurodegenerative Diseases
US-2015374737-A1 · Dec 31, 2015 · US
US9980889B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9980889-B2 |
| Application number | US-201615331711-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 21, 2016 |
| Priority date | Sep 3, 2012 |
| Publication date | May 29, 2018 |
| Grant date | May 29, 2018 |
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The present invention relates to the use of p-hydroxybenzylamine or a salt thereof as antimicrobial agent as well as to composition comprising said agent.
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The invention claimed is: 1. A cosmetic composition for topical application comprising: (i) a cosmetically acceptable carrier, (ii) at least one cosmetic agent selected from the group consisting of surfactants, emulsifiers, thickeners, and oils, and (iii) 0.001 to 10 wt.-%, based on the total weight of the composition, of a hydrochloride salt of p-hydroxybenzylamine as an antimicrobial agent. 2. The composition according to claim 1 , wherein the antimicrobial agent is present in an amount of 0.005 to 5 wt. %, based on the total weight of the composition. 3. The composition according to claim 1 , wherein the antimicrobial agent is present in an amount of 0.01 to 1 wt. %, based on the total weight of the composition. 4. The composition according to claim 1 , wherein the composition is a shampoo preparation, a hair conditioner, an O/W emulsion, a W/O emulsion or a gel. 5. The composition according to claim 1 , wherein the composition is a topical composition to be applied to human skin, scalp and/or hair. 6. A method of treating scalp, wherein the method comprises contacting the scalp with a rinse-off composition in the form of a shampoo or a conditioner comprising the cosmetic composition according to claim 1 , and thereafter rinsing the scalp with water.
Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms · CPC title
Antimicrobial preparations · CPC title
Water-in-oil emulsions, e.g. Water-in-silicone emulsions · CPC title
Amines · CPC title
Oil-in-water emulsions · CPC title
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