System and method for phase retrieval in lensless imaging

Patent metadata

Field	Value
Publication number	US-9970891-B2
Application number	US-201415033911-A
Country	US
Kind code	B2
Filing date	Nov 4, 2014
Priority date	Nov 4, 2013
Publication date	May 15, 2018
Grant date	May 15, 2018

Abstract

A method and system for use in reconstruction and retrieval of phase information associated with a two-dimensional diffractive response are presented. The method comprising: providing ( 75 ) input data indicative of one or more diffractive patterns corresponding to diffractive responses from one or more objects ( 50 ). Dividing ( 130 ) said input data into a plurality of one-dimensional slices and determining ( 140 ) one-dimensional phase data for at least some of said one-dimensional slices. Tailoring ( 150 ) the reconstructed phase data of said one-dimensional slices to form a two-dimensional phase solution. The two-dimensional phase solution is defined by phase shifts of said reconstructed one-dimensional phase data of said one-dimensional slices. The two-dimensional phase solution thus enables obtaining two-dimensional reconstructed phase data suitable for reconstruction of image data ( 250 ).

First claim

The invention claimed is:

1. A method for use in reconstruction of phase information associated with a two-dimensional diffractive response of one or more objects, the method comprising:
providing input data indicative of at least three intensity diffractive patterns associated with one or more diffractive responses from said one or more objects, such that first and second diffractive patterns are independent of one another and the third diffractive pattern includes an interference of the first and the second diffractive patterns;
dividing each of at least said independent and interfering intensity diffractive patterns into plurality of one-dimensional slices to thereby form plurality of sets of matching slices thereof; and
tailoring the one-dimensional phase data;
reconstructed from said plurality of matching slices to thereby reconstruct a two-dimensional phase data associated with said diffractive responses, said tailoring of the reconstructed one-dimensional phase data comprising determining phase shifts associated with each of said one-dimensional slices, said reconstructed two-dimensional phase data suitable for reconstruction of image data.

2. The method of claim 1 , wherein said one or more diffractive responses comprises diffractive responses of two or more objects, the method further comprising generating said input data based on said diffractive responses, said generating comprising determining cross-correlation and auto-correlation relations between said two or more objects from said diffractive responses to thereby determine intensity diffractive patterns of said objects and interference relations between said two or more objects.

3. The method of claim 1 , wherein said at least three diffractive patterns are associated with diffractive response of the one or more objects to at least three illumination channels.

4. The method of claim 3 , wherein said at least three diffractive patterns comprise data indicative of at least:
a first diffractive pattern generated by a first coherent illumination;
a second diffractive pattern generated by a second coherent illumination; and
a third diffractive pattern generated by a combination of the first and second coherent illuminations.

5. The method of claim 4 , wherein said determining reconstructed one-dimensional phase data for said plurality of one-dimensional slices comprising utilizing a cross term between said at least three diffractive patterns, said cross-term being indicative of a relative phase difference between the first and second diffractive patterns.

6. The method of claim 1 , wherein said determining said reconstructed one-dimensional phase data for each of said plurality of one-dimensional slices comprises utilizing one-dimensional vectorial phase retrieval technique.

7. The method of claim 1 ,
wherein said input data comprises a single-shot diffractive response of two or more of said objects; and wherein said method further comprises:
determining from said single-shot diffractive response, auto-correlation of said two or more objects and cross-correlation between them;
identifying intensity diffractive patterns of each of said two or more objects and interference relations between them.

8. A software product, embedded on a non-transitory computer readable medium and carrying computer readable code comprising instructions such that when operated on a computer system cause the computer system to execute method steps for use in reconstruction of phase information associated with a two-dimensional diffractive response of one or more objects, the steps comprising:
providing input data indicative of at least three intensity diffractive patterns associated with one or more diffractive responses from said one or more objects, such that first and second diffractive patterns are independent of one another and the third diffractive pattern includes an interference of the first and the second diffractive patterns;
dividing each of at least said independent and interfering intensity diffractive patterns into plurality of one-dimensional slices to thereby form plurality of sets of matching slices thereof; and
tailoring the one-dimensional phase data;
reconstructed from said plurality of matching slices to thereby reconstruct a two-dimensional phase data associated with said diffractive responses, said tailoring of the reconstructed one-dimensional phase data comprising determining phase shifts associated with each of said one-dimensional slices, said reconstructed two-dimensional phase data suitable for reconstruction of image data.

9. A system for use in phase reconstruction, the system comprising a processing utility configured for processing input data being indicative of at least three two-dimensional diffractive patterns associated with one or more diffractive responses of one or more objects, and to determine reconstructed phase data based on said input data; the processing utility comprising:
a vector generating module configured to receive said one or more diffractive responses and to generate a corresponding plurality of sets of one-dimensional vectors respectively corresponding to plurality of one-dimensional slices of said at least three two-dimensional diffractive patterns;
a one-dimensional phase reconstruction module configured to receive said sets of one-dimensional vectors, and to determine said reconstructed one-dimensional phase data associated with said sets of one-dimensional vectors; and
a two-dimensional phase tailoring module configured to perform tailoring by receiving data indicative of reconstructed one-dimensional phase data from said one-dimensional phase reconstruction module and to generate corresponding said reconstructed two-dimensional phase data indicative of reconstructed phase information associated with said input data.

10. The system of claim 9 , wherein the processing utility is configured and operable for reconstruction of phase information based on input data, said input data comprises said at least three diffractive patterns associated with said diffractive response of said one or more objects.

11. The system of claim 9 , wherein said processing utility comprises a pre-processing module configured and operable to receive and process said input data to generate data indicative of a relative phase difference between at least two diffractive patterns of said one or more two-dimensional diffractive responses.

12. The system of claim 9 , wherein the processing utility comprises a pre-processing module configured and operable to receive and process data indicative of at least one diffractive pattern associated with a diffraction response of two or more objects, said pre-processing module being configured to determine input data based on said data indicative of at least one diffractive pattern, said input data comprising diffraction pattern of each of said at least two objects and an interference relation between them.

13. The system of claim 9 configured for lens-less imaging, the system further comprising:
at least first and second illumination channels for illuminating an object to be inspected,
a detector unit comprising a pixel array for detecting scattered radiation from the object, and
a control unit configured and operable for receiving data indicative of detected scattered radiation from said detector unit and processing said data to determine reconstructed image data of said object; said control unit being configured and operable for receiving said input data being indicative of scattered light caused by the first and second illumination channels and for processing said input data to reconstruct image data indicative of the object to be inspected;

Assignees

• Yeda Res & Dev

Inventors

• Dudovich Nirit
• Raz Oren
• Nadler Boaz
• Oron Dan

Classifications

• G01N23/20

  by using diffraction of the radiation by the materials, e.g. for investigating crystal structure; by using scattering of the radiation by the materials, e.g. for investigating non-crystalline materials; by using reflection of the radiation by the materials · CPC title

• G03H5/00

  Holographic processes or apparatus using particles or using waves other than those covered by groups G03H1/00 or G03H3/00 for obtaining holograms; Processes or apparatus for obtaining an optical image from them (G03H1/22 takes precedence; construction of electron microscopes H01J37/26; {investigating or analysing materials by the use of microwaves G01N22/00, by the use of particles wave or X-rays G01N23/00, G21K7/00}) · CPC title

• G01N23/2055 Primary

  Analysing diffraction patterns · CPC title

• G03H1/0443

  Digital holography, i.e. recording holograms with digital recording means (holobject computation G03H1/0866) · CPC title

• G03H1/0866 Primary

  Digital holographic imaging, i.e. synthesizing holobjects from holograms · CPC title