System and method for mass spectrometry imaging
US-2024389905-A1 · Nov 28, 2024 · US
US9968403B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9968403-B2 |
| Application number | US-201314434038-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 16, 2013 |
| Priority date | Oct 16, 2012 |
| Publication date | May 15, 2018 |
| Grant date | May 15, 2018 |
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
What the patent document calls the invention.
A short plain-language summary of the technical disclosure.
Who owns or filed the patent and who is credited as inventor.
Filing, priority, publication, and grant dates set the timeline.
The legal scope of protection — read this for what is actually claimed.
Technology tags used to group this patent with similar filings.
Prior art links and similar publications in this corpus.
Official abstract text for this publication.
An optical device including an optical fiber having a longitudinal axis and an optical fiber core with a distal end having a distal terminating end configured to discharge a first laser energy in a first direction and a second laser energy in a second direction. The optical device also includes a fiber cap having an interior cavity and an opening to the interior cavity, where the distal end of the optical fiber core is received within the interior cavity through the opening. A cladding is included on the distal end of the optical fiber core between the optical fiber core and the fiber cap.
Opening claim text (preview).
What is claimed is: 1. An optical device comprising: an optical fiber having: (i) a longitudinal axis, and (ii) an optical fiber core configured to direct a first laser energy and a second laser energy along the longitudinal axis, the first laser energy having a first wavelength configured to perform a first treatment, and the second laser energy having a second wavelength configured to perform a second treatment; a distal end of the optical fiber core including a distal terminating end configured to discharge the first laser energy in a first direction along or parallel to the longitudinal axis, and the second laser energy in a second direction transverse with the longitudinal axis; a fiber cap comprising an interior cavity and an opening to the interior cavity, wherein the distal end of the optical fiber core is received within the interior cavity through the opening so that the first laser energy is discharged through the fiber cap in the first direction for performance of the first treatment, and the second laser energy is discharged through the fiber cap in the second direction for performance of the second treatment; a first treatment laser source configured to generate the first laser energy; a second treatment laser source configured to generate the second laser energy; a first aiming laser source configured to generate a first aiming beam having a power that does not cause tissue damage; a second aiming laser source configured to generate a second aiming beam having a power that does not cause tissue damage; and a controller coupled to the first treatment laser source, the second laser treatment source, the first aiming laser source, and the second aiming laser source, wherein the controller is configured to: in response to a request to activate the first treatment laser source, activate the first aiming laser source to deliver the first aiming beam through the fiber cap in the first direction, and then activate the first treatment laser source to deliver the first laser energy in the first direction; and in response to a request to activate the second treatment laser source, activate the second aiming laser source to deliver the second aiming beam through the fiber cap in the second direction, and then activate the second treatment laser source to deliver the second laser energy in the second direction. 2. The optical device of claim 1 , wherein the distal terminating end of the optical fiber core comprises a polished beveled surface disposed at an angle transverse to the longitudinal axis of the optical fiber. 3. The optical device of claim 2 , wherein the polished beveled surface has a coating that promotes reflection of the first laser energy off of the polished beveled surface in the first direction, and transmission of the second laser energy through the polished beveled surface in the second direction. 4. The optical device of claim 3 , wherein the coating is a dichroic coating that reflects the first laser energy and transmits the second laser energy. 5. An optical device, comprising: a first treatment laser source configured to generate a first laser energy; a second treatment laser source configured to generate a second laser energy; a first aiming laser source configured to generate a first aiming beam having a wavelength from 300 nm to 600 nm, the first aiming beam having a power that does not cause tissue damage; a second aiming laser source configured to generate a second aiming beam having a wavelength from 1900 nm to 2100 nm, the second aiming beam having a power that does not cause tissue damage; an optical fiber having: (i) a longitudinal axis, and (ii) an optical fiber core configured to direct the first laser energy and the second laser energy along the longitudinal axis, the first laser energy having a first wavelength configured to perform a first treatment, and the second laser energy having a second wavelength configured to perform a second treatment, wherein the first and second treatments are different, the first treatment is configured to affect bodily tissues by ablating tissue, and the second treatment is configured to affect bladder or kidney stones by ablating the bladder or kidney stones; a distal end of the optical fiber core including a distal terminating end configured to discharge the first laser energy in a first direction along or parallel to the longitudinal axis, and the second laser energy in a second direction transverse with the longitudinal axis; a fiber cap comprising an interior cavity and an opening to the interior cavity, wherein the distal end of the optical fiber core is received within the interior cavity through the opening so that the first laser energy is discharged through the fiber cap in the first direction for performance of the first treatment, and the second laser energy is discharged through the fiber cap in the second direction for performance of the second treatment; and a controller coupled to the first treatment laser source, the second laser treatment source, the first aiming laser source, and the second aiming laser source, wherein: the distal terminating end of the optical fiber core comprises a polished beveled surface disposed at an angle transverse to the longitudinal axis of the optical fiber; the distal terminating end is configured to discharge the first aiming beam through the fiber cap in the first direction and the second aiming beam through the fiber cap in the second direction; each of the first and second aiming beams are configured to indicate a wavelength for the respective first and second laser energies; in response to a request to activate the first treatment laser source, the controller is configured to activate the first aiming laser source to deliver the first aiming beam through the fiber cap in the first direction, and then activate the first treatment laser source to deliver the first laser energy in the first direction; in response to a request to activate the second treatment laser source, the controller is configured to activate the second aiming laser source to deliver the second aiming beam through the fiber cap in the second direction, and then activate the second treatment laser source to deliver the second laser energy in the second direction; the polished beveled surface has a coating that promotes reflection of the first laser energy and the first aiming beam off of the polished beveled surface in the first direction based on the wavelength of the first laser energy and the first aiming beam, respectively, and transmission of the second laser energy and the second aiming beam through the polished beveled surface in the second direction based on the wavelength of the second laser energy and the second aiming beam, respectively; the fiber cap is bonded to the optical fiber so as to seal the interior cavity, and the sealed interior cavity includes at least one of a gas, a liquid, or a vacuum configured to promote total internal reflection of the first laser energy off of the polished beveled surface; the coating is a dichroic coating that reflects the first laser energy and transmits the second laser energy; and the first wavelength is in the range of 300-600 nm, and the second wavelength is in the range of 1900-2100 nm. 6. The optical device of claim 1 , wherein the first and second treatments are different. 7. The optical device of claim 6 , wherein the first treatment affects bodily tissues and the second treatment affects bladder or kidney stones. 8. The optical device of claim 1 , wherein the distal terminating end is configured to discharge the first aiming beam through the fiber cap in the first direction and the second aiming beam through the fiber cap in the second direction. 9. The optical device of
with reflective or refractive surfaces for deflecting the beam (A61B2018/2261, A61B2018/2266 take precedence) · CPC title
Vaporization · CPC title
Alarms or notifications created in response to an abnormal condition · CPC title
Coagulation · CPC title
with a lens, e.g. ball tipped · CPC title
Related publications grouped by family.
Answers are generated from the same data shown on this page.