Cartridge systems useful in cleaning dialysis solutions

Patent metadata

Field	Value
Publication number	US-9962477-B2
Application number	US-201514983942-A
Country	US
Kind code	B2
Filing date	Dec 30, 2015
Priority date	Dec 30, 2015
Publication date	May 8, 2018
Grant date	May 8, 2018

Abstract

Sorbent cartridge systems useful in regenerating or purifying dialysis solutions are described as well as methods to regenerate or purify spent dialysis solutions. Dialysis systems using the sorbent cartridge system of the present invention are further described.

First claim

What is claimed is:

1. A sorbent cartridge system, comprising:
a sorbent cartridge comprising i) a continuous sidewall extending between a fluid inlet and a fluid outlet, which define a chamber, ii) at least one layer comprising solid particulate media, wherein the at least one layer extends across the chamber within the continuous sidewall, and the at least one layer comprises a first region and a second region adjacent the first region and located closer to the continuous sidewall than the first region; and
an intake manifold comprising at least one first discharge port and at least one second fluid discharge port, wherein the intake manifold and sorbent cartridge are positionable with respect to each other to locate the first region of the sorbent cartridge for fluid communication with the at least one first discharge port and locate the second region of the sorbent cartridge for fluid communication with the at least one second fluid discharge port, wherein the intake manifold is configured wherein a first volumetric flow rate of fluid discharged at the first fluid discharge port into the first region is greater as compared to a second volumetric flow rate of fluid discharged at the second fluid discharge port into the second region,
wherein the intake manifold comprises i) at least one central branch passageway comprising a first hydraulic diameter and the at least one first discharge port, ii) at least one peripheral branch passageway comprising a second hydraulic diameter and the at least one second discharge port, and iii) a fluid feeding passageway for supplying fluid concurrently to the at least one central branch passageway and the at least one peripheral branch passageway, wherein the first hydraulic diameter of the at least one central branch passageway is greater than the second hydraulic diameter of the at least one peripheral branch passageway.

2. The system of claim 1 , wherein the at least one peripheral branch passageway comprises a plurality of pipes having discharge openings arranged in spaced-apart pattern around the at least one discharge port of the at least one central branch passageway, wherein each of the plurality of pipes having the second hydraulic diameter.

3. The system of claim 1 , wherein the at least one peripheral branch passageway comprises a single duct having a continuous discharge opening which is arranged around and radially spaced from the at least one discharge port of the at least one central branch passageway, wherein the single duct having the second hydraulic diameter.

4. A sorbent cartridge system, comprising:
a sorbent cartridge comprising i) a continuous sidewall extending between a fluid inlet and a fluid outlet, which define a chamber, ii) at least one layer comprising solid particulate media, wherein the at least one layer extends across the chamber within the continuous sidewall, and the at least one layer comprises a first region and a second region adjacent the first region and located closer to the continuous sidewall than the first region; and
an intake manifold comprising at least one first discharge port and at least one second fluid discharge port, wherein the intake manifold and sorbent cartridge are positionable with respect to each other to locate the first region of the sorbent cartridge for fluid communication with the at least one first discharge port and locate the second region of the sorbent cartridge for fluid communication with the at least one second fluid discharge port, wherein the intake manifold is configured wherein a first volumetric flow rate of fluid discharged at the first fluid discharge port into the first region is greater as compared to a second volumetric flow rate of fluid discharged at the second fluid discharge port into the second region, wherein the intake manifold comprises concentric tubes comprising i) an inner tube comprising a first hydraulic diameter, the at least one first discharge port, and at least one first fluid supply inlet port, ii) an outer tube concentrically surrounding the inner tube, wherein the outer tube comprising a second hydraulic diameter, the at least one second discharge port, and at least one second fluid supply inlet port, iii) a fluid feeding passageway for supplying fluid concurrently to the at least one first fluid supply inlet port of the inner tube and the at least one second fluid supply inlet port of the outer tube, wherein the first hydraulic diameter of the inner tube is greater than the second hydraulic diameter of the outer tube.

5. A sorbent cartridge system, comprising:
a sorbent cartridge comprising i) a continuous sidewall extending between a fluid inlet and a fluid outlet, which define a chamber, ii) at least one layer comprising solid particulate media, wherein the at least one layer extends across the chamber within the continuous sidewall, and the at least one layer comprises a first region and a second region adjacent the first region and located closer to the continuous sidewall than the first region; and
an intake manifold comprising at least one first discharge port and at least one second fluid discharge port, wherein the intake manifold and sorbent cartridge are positionable with respect to each other to locate the first region of the sorbent cartridge for fluid communication with the at least one first discharge port and locate the second region of the sorbent cartridge for fluid communication with the at least one second fluid discharge port, wherein the intake manifold is configured wherein a first volumetric flow rate of fluid discharged at the first fluid discharge port into the first region is greater as compared to a second volumetric flow rate of fluid discharged at the second fluid discharge port into the second region, wherein the intake manifold comprises a spray nozzle head comprising i) a housing defining a fluid chamber which is fluidly linkable with a fluid supply line and an open side, and ii) a perforated plate covering the open side of the housing, wherein the perforated plate comprises (a) a first central region comprising a first perforated plate portion defining a plurality of first holes passing through a first solid plate portion, wherein the first holes have a first diameter, and (b) a second peripheral region which surrounds the first central region, wherein the second peripheral region comprising a second perforated plate portion defining a plurality of second holes passing through a second solid plate portion, wherein the second holes have a second diameter, and wherein the first diameter of the first holes are larger than the second diameter of the second holes, and the at least one first discharge port comprises the first holes and the at least one second discharge port comprises the second holes.

6. The system of claim 1 , wherein the intake manifold is configured wherein the first volumetric flow rate of fluid discharged at the first fluid discharge port into the first region is at least 5% greater as compared to the second volumetric flow rate of fluid discharged at the second fluid discharge port into the second region.

7. The system of claim 1 , wherein the intake manifold is configured wherein the first volumetric flow rate of fluid discharged at the first fluid discharge port into the first region is at least 10% greater as compared to the second volumetric flow rate of fluid discharged at the second fluid discharge port into the second region.

8. The system of claim 1 , wherein the first region comprises first solid particulate media having a first average packing density, and the second region comprises second solid particulate media having a second average packing density, wherein the first average packing density is within ±1% of the second average packing density.

9. The sy

Assignees

• Fresenius Medical Care Holdings Inc

Inventors

• Slade Charles J

Classifications

• B01J31/003

  containing enzymes · CPC title

• A61M2206/18

  Coaxial flows, e.g. one flow within another · CPC title

• A61M1/1696 Primary

  with dialysate regeneration · CPC title

• B01J41/02

  Processes using inorganic exchangers · CPC title

• C02F2201/006

  Cartridges · CPC title