Transcriptional control in Alicyclobacillus acidocaldarius and associated genes, proteins, and methods

US9957510B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9957510-B2
Application numberUS-201615347936-A
CountryUS
Kind codeB2
Filing dateNov 10, 2016
Priority dateFeb 22, 2008
Publication dateMay 1, 2018
Grant dateMay 1, 2018

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

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Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of modulating transcription or transcription or transcriptional control using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.

First claim

Opening claim text (preview).

What is claimed is: 1. An expression vector comprising a nucleic acid encoding a polypeptide having at least 90% sequence identity to SEQ ID NO: 1514 and wherein the polypeptide is a ribose operon repressor. 2. The expression vector of claim 1 , wherein the polypeptide is a central glycolytic genes regulator at a temperature at or above 50 degrees Celsius. 3. The expression vector isolated of claim 1 , wherein the polypeptide has 100% identity to SEQ ID NO: 1514. 4. The expression vector isolated of claim 1 , wherein the nucleic acid has at least 90% identity to SEQ ID NO: 1515. 5. The expression vector isolated of claim 1 , wherein the nucleic acid has 100% identity to SEQ ID NO: 1515. 6. A cell comprising the expression vector of claim 1 . 7. A method of modulating transcription or transcriptional control at temperatures at or above 25 degrees Celsius, the method comprising providing to a transcriptional system the expression vector of claim 1 . 8. The method according to claim 7 , wherein providing to a transcriptional system the expression vector of claim 1 occurs at a temperature at or above 50 degrees Celsius.

Assignees

Inventors

Classifications

  • Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora · CPC title

  • C12N15/635Primary

    Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline · CPC title

  • from bacteria · CPC title

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What does patent US9957510B2 cover?
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of modulating transcription or transcription or transcriptional control using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
Who is the assignee on this patent?
Battelle Energy Alliance Llc
What technology area does this patent fall under?
Primary CPC classification C12N15/635. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue May 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).