Shroud deployment in automatic injection devices

Patent metadata

Field	Value
Publication number	US-9956353-B2
Application number	US-201214007849-A
Country	US
Kind code	B2
Filing date	Mar 29, 2012
Priority date	Mar 29, 2011
Publication date	May 1, 2018
Grant date	May 1, 2018

Abstract

Exemplary embodiments provide automatic injection devices in which a shroud is automatically deployed to protectively sheath a needle after an injection is performed. Exemplary embodiments also provide shroud deployment assemblies including a shroud and a syringe carrier that, when cooperatively configured in an automatic injection device, ensure that the shroud is automatically and completely deployed after an injection is performed using the automatic injection device. Exemplary embodiments are also configured to ensure that, once the shroud is deployed to an extended position to sheath the needle, accidental forces applied to the shroud do not succeed in subsequently retracting the shroud to a retracted position in which the needle would become exposed.

First claim

What is claimed is:

1. A shroud deployment assembly for use in an automatic injection device, the shroud deployment assembly comprising:
a shroud disposed within an internal bore of a housing of the automatic injection device, the shroud movable between a retracted position and an extended position relative to the housing, the shroud comprising:
a tubular member extending between a proximal end and a distal end, and
one or more arms extending from the distal end of the tubular member; and

a syringe carrier coupled to and disposed partly within the tubular member of the shroud, the syringe carrier comprising a cylindrical portion having a slot forming a trench in an outer surface of the cylindrical portion extending along a length of the syringe carrier;
wherein, as the shroud is deployed from the retracted position to the extended position, the one or more arms of the shroud move forwardly within a constrained space formed between an inner surface of the housing of the automatic injection device and an outer surface of the cylindrical portion of the syringe carrier to engage with the trench as they move forwardly; and
wherein the trench is configured to facilitate smooth movement of the one or more arms of the shroud within the constrained space during deployment of the shroud.

2. The shroud deployment assembly of claim 1 , wherein the height of the constrained space is configured to be at least equal to a thickness of the one or more arms of the shroud.

3. The shroud deployment assembly of claim 1 , wherein an outer diameter of the cylindrical portion of the syringe carrier is configured to range from about 13.0 mm to about 14.0 mm.

4. The shroud deployment assembly of claim 1 , wherein a thickness of the one or more arms of the shroud is configured to reduce a pinching effect of the one or more arms during movement of the one or more arms in the constrained space.

5. The shroud deployment assembly of claim 4 , wherein the thickness of the one or more arms of the shroud is configured to be at most equal to the height of the constrained space.

6. The shroud deployment assembly of claim 5 , wherein the thickness of the one or more arms of the shroud is configured to range from about 1.3 mm to about 1.4 mm.

7. The shroud deployment assembly of claim 1 , wherein an inner diameter of the housing of the automatic injection device is configured to range from about 17 mm to about 18 mm.

8. The shroud deployment assembly of claim 1 , wherein the cylindrical portion of the syringe carrier comprises:
a proximal tubular portion having a first outer diameter;
a distal tubular portion having a second outer diameter less than the first diameter; and
a chamfered relief formed between the proximal and distal tubular portions.

9. The shroud deployment assembly of claim 8 , wherein the chamfered relief has an angle ranging from about 5 degrees to about 60 degrees.

10. The shroud deployment assembly of claim 1 , wherein the trench has a depth ranging from about 0.1 mm to about 0.5 mm.

11. The shroud deployment assembly of claim 1 , wherein the shroud, in the extended position, protectively sheathes a needle disposed at a proximal end of the automatic injection device, and wherein the shroud, in the retracted position, allows exposure of a needle disposed at a proximal end of the automatic injection device.

12. The shroud deployment assembly of claim 1 , wherein, once the shroud is deployed to the extended position, the shroud is configured to withstand a force of at least 80 N without retracting to the retracted position.

13. The shroud deployment assembly of claim 1 , further comprising:
a biasing mechanism that is in a compressed state when the shroud is in the retracted position and that automatically biases the shroud from the retracted position to the extended position after the automatic injection device is removed from an injection site.

14. The shroud deployment assembly of claim 1 , wherein the automatic injection device comprises a dose of a TNFα inhibitor.

15. The shroud deployment assembly of claim 14 , wherein the TNFα inhibitor is a human TNFα antibody, or antigen-binding portion thereof.

16. The shroud deployment assembly of claim 15 , wherein the human TNFα antibody, or antigen-binding portion thereof, is adalimumab or golimumab.

17. An automatic injection device, comprising:
a housing having an internal bore extending between a proximal end and a distal end;
a shroud disposed within the internal bore at the proximal end of the housing of the automatic injection device, the shroud movable between a retracted position and an extended position relative to the housing, the shroud comprising:
a tubular member extending between a proximal end and a distal end, and
one or more arms extending from the distal end of the tubular member; and

a syringe carrier disposed partly within the tubular member of the shroud, the syringe carrier comprising a tubular member having a slot forming a trench in an outer surface thereof extending along a length of the syringe carrier;
wherein, as the shroud is deployed from the retracted position to the extended position, the one or more arms of the shroud move forwardly within a constrained space formed between an inner surface of the housing of the automatic injection device and an outer surface of the tubular member of the syringe carrier to engage with the trench; and
wherein the trench is configured to facilitate movement of the one or more arms of the shroud within the constrained space during deployment of the shroud.

18. The automatic injection device of claim 17 , wherein the height of the constrained space is configured to be at least equal to a thickness of the one or more arms of the shroud.

19. The automatic injection device of claim 17 , wherein an outer diameter of the tubular member of the syringe carrier is configured to range from about 13.0 mm to about 14.0 mm.

20. The automatic injection device of claim 17 , wherein a thickness of the one or more arms of the shroud is configured to reduce the pinching effect of the one or more arms during its movement in the constrained space.

21. The automatic injection device of claim 20 , wherein the thickness of the one or more arms of the shroud is configured to be at most equal to the height of the constrained space.

22. The automatic injection device of claim 21 , wherein the thickness of the one or more arms of the shroud is configured to range from about 1.3 mm to about 1.4 mm.

23. The automatic injection device of claim 17 , wherein an inner diameter of the housing of the automatic injection device is configured to range from about 17 mm to about 18 mm.

24. The automatic injection device of claim 17 , wherein the tubular member of the syringe carrier comprises:
a proximal tubular portion having a first diameter;
a distal tubular portion having a second diameter less than the first diameter; and
a chamfered relief formed between the proximal and distal tubular portions.

25. The automatic injection device of claim 24 , wherein the chamfered relief has an angle ranging from about 5 degrees to about 60 degrees.

26. The automatic injection device of claim 17 , wherein the trench has a depth ranging from about 0.1 mm to about 0.5 mm.

27. The automatic injection device of claim 17 , wherein the shroud, in the extended position, protectively sheathes a needle disposed at a proxi

Assignees

• Rao Vivek
• Shang Sherwin
• Ozdaryal Esra
• Tsvirko Eduard
• Chim Edwin
• Post David
• Dipalma Vincent
• Abbvie Inc

Inventors

• Rao Vivek
• Shang Sherwin
• Ozdaryal Esra
• Tsvirko Eduard
• Chim Edwin
• Post David
• Dipalma Vincent

Classifications

• A61P37/06

  Immunosuppressants, e.g. drugs for graft rejection · CPC title

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P29/00

  Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

• A61M5/3204

  Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices · CPC title

• A61M2005/206

  With automatic needle insertion · CPC title