Crystalline forms of ras inhibitors, compositions containing the same, and methods of use thereof
US-2024352036-A1 · Oct 24, 2024 · US
US9956262B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9956262-B2 |
| Application number | US-201414893366-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 23, 2014 |
| Priority date | May 24, 2013 |
| Publication date | May 1, 2018 |
| Grant date | May 1, 2018 |
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The present invention relates to an isolated bacterium from the genus Pseudoalteromonas for its use as a probiotic, the use of said strain as a preservative, cyclolipopeptides which may be obtained from this bacterium, a composition comprising at least such a cyclolipopeptide, as well as to their uses.
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The invention claimed is: 1. A method of treatment to improve animal breeding, which comprises the administration of an effective amount of an isolated bacterium Pseudoalteromonas hCg-6 , capable of producing cyclolipopeptides or formula A: wherein: R is selected from the group consisting of (a) alkyl groups comprising between 4 and 20 carbon atoms, except nonyl and undecyl groups; (b) alkylene groups comprising between 4 and 20 carbon atoms, except undec-4-ylene and tridec-6 -ylene groups; (c) alkyl groups substituted with an —OH group and comprising between 4 and 20 carbon atoms; and (d) alkylene groups substituted with an —OH group and comprising between 4 and 20 carbon atoms. 2. The method according to claim 1 , wherein the isolated bacterium is Pseudoalteromonas hCg-6 , a strain deposited according to the Budapest Treaty, on May 22, 2013, at the Collection Nationale de Culture de Microorganismes (CNCM, Paris, France) under the number I-4753. 3. The method of claim 1 , wherein the animal breeding occurs in aquaculture. 4. The method of claim 1 , wherein the animal is a fish, shellfish, crustacean, abalone or oyster.
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