Image obtaining apparatus and stage control method

Patent metadata

Field	Value
Publication number	US-9952420-B2
Application number	US-201414168883-A
Country	US
Kind code	B2
Filing date	Jan 30, 2014
Priority date	Feb 7, 2013
Publication date	Apr 24, 2018
Grant date	Apr 24, 2018

Abstract

An image obtaining apparatus includes an image pickup unit, a stage, a connection unit, a movement mechanism, a position detection unit, and a control unit. The image pickup unit includes an objective lens. The stage is configured to determine a position of a pathology slide in an optical axis direction of the objective lens, and the pathology slide is an image pickup target of the image pickup unit. The connection unit is provided to the stage. The movement mechanism is connected to the stage through the connection unit and configured to move the stage in the optical axis direction. The position detection unit is configured to detect a position of the stage in the optical axis direction for a measurement point preset on the stage. The control unit is configured to control the movement mechanism by using at least a result of the detection by the position detection unit.

First claim

What is claimed is:

1. An image obtaining apparatus, comprising:
an image pickup unit including an objective lens;
a stage configured to position a pathology slide with respect to the image pickup unit and in a direction of an optical axis of the objective lens;
a connection unit coupled to the stage;
a movement mechanism including a stepper motor, wherein the movement mechanism is coupled to the connection unit and configured to move the stage in the optical axis direction;
a position detection unit configured to detect a current position of the stage in the optical axis direction; and
a control unit configured to:
calculate a plurality of target positions including a first target position, a second target position, and a third target position, each target position of the plurality of target positions corresponding to a different unit of time in a series, wherein each unit of time is less than a period of time to move the stage from an initial starting position to a final image pickup position where an image of the pathology slide is taken,
calculate a first difference between the first target position for a first unit of time in the series and the second target position for a second unit of time in the series, wherein the second unit of time in the series precedes the first unit of time in the series,
convert the first difference to a first control amount,
calculate a second difference between the third target position for a third unit of time in the series and the current position of the stage in the optical axis direction as detected by the position detection unit, wherein the third unit of time in the series precedes the first unit of time in the series by n units of time, and wherein n is a positive integer greater than two,
convert the second difference to a second control amount,
synthesize the first control amount and the second control amount to determine a third control amount, and
output one or more drive pulses to the stepper motor based on the third control amount,
wherein the image pickup unit acquires an image of the pathology slide at the final image pickup position.

2. The image obtaining apparatus according to claim 1 , wherein the connection unit protrudes from the stage in the optical axis direction.

3. A stage control method, comprising:
detecting a current position of a stage in an optical axis direction of an objective lens of an image pickup unit;
calculating a plurality of target positions including a first target position, a second target position, and a third target position, each target position of the plurality of target positions corresponding to a different unit of time in a series, wherein each unit of time is less than a time period to move the stage from an initial starting position to a final image pickup position for an image of a pathology slide;
calculating a first difference between the first target position for a first unit of time in the series and the second target position for a second unit of time in the series, wherein the second unit of time in the series precedes the first unit of time in the series;
converting the first difference to a first control amount;
calculating a second difference between the third target position for a third unit of time in the series and the current position of the stage in the optical axis direction as detected by the position detection unit, wherein the third unit of time in the series precedes the first unit of time in the series by n units of time, and wherein n is a positive integer greater than two;
converting the second difference to a second control amount;
synthesizing the first control amount and the second control amount to determine a third control amount; and
outputting one or more drive pulses based on the third control amount to a stepper motor coupled to the stage thereby moving the stage in the optical axis direction of the objective lens.

4. An image obtaining apparatus, comprising:
an image pickup unit that includes an objective lens;
a stage that positions a pathology slide with respect to the image pickup unit and in a direction of an optical axis of the objective lens;
a connection unit coupled to the stage;
a movement mechanism including a stepper motor, wherein the movement mechanism is coupled to the connection unit and moves the stage in the optical axis direction;
a position detection unit that detects a current position of the stage in the optical axis direction;
a control unit that:
calculates a plurality of target positions including a first target position, a second target position, and a third target position, each target position of the plurality of target positions corresponding to a different unit of time in a series, wherein each unit of time is less than a period of time to move the stage from an initial starting position to a final image pickup position where an image of the pathology slide is taken,
calculates a first difference between the first target position for a first unit of time in the series and the second target position for a second unit of time in the series, wherein the second unit of time in the series precedes the first unit of time in the series,
converts the first difference to a first control amount,
calculates a second difference between a third target position for a third unit of time in the series and the current position of the stage in the optical axis direction as detected by the position detection unit, wherein the third unit of time in the series precedes the first unit of time in the series by n units of time, and wherein n is a positive integer greater than two,
converts the second difference to a second control amount, and
synthesizes the first control amount and the second control amount to determine a third control amount; and

a sequencer that outputs one or more drive pulses to the stepper motor based on the third control amount,
wherein the image pickup unit acquires an image of the pathology slide at the final image pickup position.

5. The image obtaining apparatus according to claim 4 , wherein the connection unit protrudes from the stage in the optical axis direction.

Assignees

• Sony Corp

Inventors

• Suzuki Fumiyasu

Classifications

• G05B19/10

  using selector switches · CPC title

• G02B21/362

  Mechanical details, e.g. mountings for the camera or image sensor, housings (G02B21/364 takes precedence) · CPC title

• H02P8/14

  Arrangements for controlling speed or speed and torque (H02P8/12, H02P8/22 take precedence) · CPC title

• G02B21/26 Primary

  Stages; Adjusting means therefor · CPC title