Methods and apparatus for ascertaining specimen and/or sample container characteristics while in transit

Patent metadata

Field	Value
Publication number	US-9952241-B2
Application number	US-201314422903-A
Country	US
Kind code	B2
Filing date	Aug 20, 2013
Priority date	Aug 20, 2012
Publication date	Apr 24, 2018
Grant date	Apr 24, 2018

Abstract

Methods of identifying a characteristic of a clinical analysis specimen or a sample container containing the specimen are disclosed. The methods include moving the sample container along a track while causing translation and rotation of the sample container, and capturing two or more images of the sample container during the translation and rotation. The track may have one or more moveable belts contacting a carrier to rotate and translate the carrier holding the sample container. Image analysis may be used to read a barcode label of the sample container, determine HIL, and/or physical characteristics of the sample container. Apparatus for carrying out the method are described, as are other aspects.

First claim

What is claimed is:

1. A method of determining a characteristic of a sample container or a specimen contained within the sample container, comprising:
translating the sample container along a track while the sample container is in the field of view of an imaging apparatus;
contacting a carrier holding the sample container between a first horizontally-movable member and a wall;
rotating the sample container while the sample container is in the field of view of the imaging apparatus by moving the first horizontally-movable member relative to the carrier and the wall; and
capturing two or more images of the sample container with the imaging apparatus during the translation and rotation of the sample container.

2. The method of claim 1 , comprising causing simultaneous translation and rotation of the sample container while the sample container is in the field of view of the imaging apparatus.

3. The method of claim 1 , comprising analyzing at least one of the two or more images to determine a presence of one or more interferents within the specimen.

4. The method of claim 3 , wherein the one or more interferents comprise:
an amount of lipemia in a serum or plasma portion of the specimen;
an amount of hemolysis in a serum or plasma portion of the specimen; or
an amount of icterus in a serum or plasma portion of the specimen.

5. The method of claim 1 , comprising analyzing at least one of the two or more images to read a barcode on the sample container.

6. The method of claim 1 , comprising analyzing at least one of the two or more images to determine a characteristic of the sample container.

7. The method of claim 1 , wherein the capturing an image further comprises:
illuminating the sample container during the translation and rotation of the sample container while the sample container is in the field of view of the imaging apparatus.

8. The method of claim 1 , wherein the capturing an image further comprises:
providing an imaging background and imaging the sample container against the imaging background during the translation and rotation.

9. The method of claim 1 , wherein the first horizontally-moveable member is a first horizontally-moveable belt, and wherein the wall is a second horizontally-movable belt, and wherein rotating the sample container comprises:
contacting a first side of a carrier holding the sample container with the first horizontally-moveable belt;
contacting a second side of the carrier with the second horizontally-moveable belt; and
rotating the sample container by moving the first horizontally-moveable belt and the second horizontally-moveable belt relative to the carrier.

10. The method of claim 1 , wherein the wall is a stationary wall, and wherein rotating the sample container comprises:
contacting a first side of a carrier holding the sample container with the first horizontally-moveable member;
contacting a second side of the carrier holding the sample container with the stationary wall; and
rotating the sample container by moving the first horizontally-moveable member relative to the stationary wall and the carrier.

11. The method of claim 1 , wherein the wall is a second horizontally-movable member, and comprising contacting the carrier holding the sample container between the first horizontally-moveable member and the second horizontally-moveable member, and at least one of:
moving the first horizontally-moveable member and the second horizontally-moveable member in opposite directions;
moving the first horizontally-moveable member and the second horizontally-moveable member in a same direction but at different speeds;
moving one of the first horizontally-moveable member or the second horizontally-moveable member; and
solely translating the carrier holding the sample container at certain times, solely rotating the carrier at certain times, and rotating and translating the carrier at other times.

12. An identification apparatus, comprising:
a track adapted to cause translation of a carrier holding a sample container containing a specimen;
a wall adapted to contact the carrier;
a horizontally-moveable member adapted to contact the carrier, wherein the carrier is configured to be located between the wall and the horizontally-movable member, and wherein the carrier is configured to be rotated by movement of the horizontally-moveable member relative to the carrier and the wall; and
an imaging apparatus adapted to capture two or more images of the sample container during the translation and rotation.

13. The apparatus of claim 12 , comprising an illumination source adapted to illuminate the sample container.

14. The apparatus of claim 12 , comprising an imaging background, wherein the sample container is located between a camera of the imaging apparatus and the imaging background during the translation and rotation.

15. The apparatus of claim 12 , comprising an image processor adapted to analyze the two or more images.

16. The apparatus of claim 15 , wherein the image processor analyzes at least one of the two or more images to determine a presence of one or more interferents within the specimen.

17. The apparatus of claim 15 , wherein the image processor analyzes at least one of the two or more images to read a barcode on the sample container.

18. The apparatus of claim 15 , wherein the image processor analyzes at least one of the two or more images to determine a characteristic of the sample container.

19. An identification system, comprising:
a carrier adapted to hold a sample container containing a specimen;
a track adapted to cause translation of the carrier;
a first horizontally-moveable belt adapted to contact a vertical side of the carrier;
a second horizontally-moveable belt adapted to contact a vertical side of the carrier, wherein the carrier is adapted to be located between the first horizontally-moveable belt and the second horizontally-moveable belt, and wherein the carrier is configured to be rotated by movement of the first horizontally-moveable belt relative to the second horizontally-moveable belt; and
an imaging apparatus having an image field adapted to capture at least two images of the sample container during the translation and rotation.

Assignees

• Miller Kerry L
• Siemens Healthcare Diagnostics Inc

Inventors

• Miller Kerry L

Classifications

• G01N21/84

  Systems specially adapted for particular applications · CPC title

• G01N2201/062

  LED's · CPC title

• G01N2021/845

  Objects on a conveyor · CPC title

• G01N2035/00752

  bar codes · CPC title

• G01N35/02 Primary

  using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations {(G01N35/0098 and G01N35/0099 take precedence)} · CPC title