Dose setting mechanism for priming a drug delivery device

Patent metadata

Field	Value
Publication number	US-9950116-B2
Application number	US-78868310-A
Country	US
Kind code	B2
Filing date	May 27, 2010
Priority date	Jun 1, 2009
Publication date	Apr 24, 2018
Grant date	Apr 24, 2018

Abstract

A method and system for providing a drug delivery device. The drug delivery device comprises a dose setting mechanism comprising a spindle and a cartridge holder coupled to the dose setting mechanism. The cartridge holder comprising a cartridge having a movable bung at one end of the cartridge. The cartridge holder must be rotated before a dose may set with the dose setting mechanism.

First claim

The invention claimed is:

1. A priming mechanism for a drug delivery device, said priming mechanism comprising:
a dose setting mechanism comprising
a spindle; and
a dose dial sleeve;
a cartridge holder, said cartridge holder comprising a cartridge, said cartridge comprising a movable bung near a proximal end of said cartridge;
a coupling part connecting said cartridge holder to said dose dial sleeve of said dose setting mechanism, and
a spindle nut rotationally coupled to said coupling part, said spindle nut coupling said cartridge holder to said spindle of said dose setting mechanism;
such that when said cartridge holder is rotated with respect to said dose setting mechanism,
said spindle nut is rotated and moves said spindle into an abutting engagement with said bung so as to prime the drug delivery device, and
wherein said dose setting mechanism comprises at least one flexible locking element,
wherein when said cartridge holder is rotated, said coupling part also rotates to thereby release said at least one flexible locking element and allowing said dose dial sleeve to rotate and allow a user of said medical delivery device to set a dose.

2. The invention of claim 1 wherein said coupling part comprises a thin metal pressing.

3. The invention of claim 1 wherein said coupling part comprises a rigid coupling component.

4. The invention of claim 1 wherein said spindle nut further comprises a plurality of helical ramps,
said plurality of helical ramps driving said spindle nut in said distal direction when said cartridge holder is rotated so that said spindle abuts a first surface of said bung.

5. A dose setting mechanism for priming a drug delivery device,
said dose setting mechanism configured to be coupled to a cartridge holder comprising a cartridge, said cartridge comprising a movable bung, said dose setting mechanism comprising:
a spindle; and
a dose dial sleeve;
a coupling part configured to connect said cartridge holder to said dose dial sleeve, and
a spindle nut rotationally coupled to said coupling part, said spindle nut coupling said cartridge holder to said spindle of said dose setting mechanism;
such that when said cartridge holder is rotated with respect to said dose setting mechanism,
said spindle nut is rotated, wherein said coupling part unlocks said dose dial sleeve so that said dose dial sleeve may be rotated to set a dose, wherein said cartridge holder must be rotated with respect to said dose setting mechanism before said dose may be set with said dose setting mechanism
wherein said dose setting mechanism comprises at least one flexible locking element,
wherein when said cartridge holder is rotated, said coupling part also rotates to thereby release said at least one flexible locking element and allowing said dose dial sleeve to rotate and allow a user of said medical delivery device to set a dose.

6. The dose setting mechanism of claim 5 wherein
when said cartridge holder is rotated with respect to said dose setting mechanism,
said spindle nut is rotated,
and moves said spindle into an abutting engagement with said bung.

7. The dose setting mechanism of claim 5 wherein said coupling part comprises a thin metal pressing.

8. The dose setting mechanism of claim 5 wherein said coupling part comprises a rigid coupling component.

9. The dose setting mechanism of claim 5 wherein said spindle nut further comprises a plurality of helical ramps,
said plurality of helical ramps driving said spindle nut in said distal direction when said cartridge holder is rotated so that said spindle abuts a first surface of said bung.

10. The dose setting mechanism of claim 5 wherein rotation of said cartridge holder from a first position to a second position primes said drug delivery device.

11. The dose setting mechanism of claim 10 wherein after said cartridge holder is rotated from the first position to the second position, said cartridge holder is rotationally locked to said dose setting mechanism.

12. The dose setting mechanism of claim 11 wherein said cartridge holder is rotationally locked to said dose setting mechanism by way of a one way, non-return detent feature.

13. The dose setting mechanism of claim 5 wherein said dose setting mechanism comprises, along an outer surface of the dose setting mechanism, a marking indicating an unprimed state and a marking indicating a primed stated, and
wherein said cartridge holder comprises a positional indicator that indicates a relative position of the cartridge housing with respect to the outer surface of the dose setting mechanism.

Assignees

• Plumptre David Aubrey
• Davies James Alexander
• Jones Christopher John
• Veasy Robert Frederick
• Sanofi Aventis Deutschland

Inventors

• Plumptre David Aubrey
• Davies James Alexander
• Jones Christopher John
• Veasy Robert Frederick

Classifications

• A61M5/24 Primary

  Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic {(ampoules or carpules A61J1/06)} · CPC title

• A61M5/31543

  piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change · CPC title

• A61M2005/2492

  via snap connection · CPC title

• A61M5/31551

  including axial movement of dose setting member · CPC title

• A61M5/3146

  Priming, e.g. purging, reducing backlash or clearance · CPC title