Method for the synthesising 4-piperidin-4-yl-benzene-1,3-diol and the salts of same and novel compound tert-butyl 4-(2,4-dihydroxy-phenyl)-4-hydroxy-piperidine-1-carboxylate
US-2015376126-A1 · Dec 31, 2015 · US
US9944600B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9944600-B2 |
| Application number | US-201314407214-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 11, 2013 |
| Priority date | Jun 12, 2012 |
| Publication date | Apr 17, 2018 |
| Grant date | Apr 17, 2018 |
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The present invention relates to novel piperidine derivatives, stereoisomers thereof or pharmaceutically acceptable salts thereof; methods for preparing the compound; and pharmaceutical compositions comprising the compound. The novel piperidine derivatives, according to the present invention, having an effect as GPR119 agonist can be used for treatment of metabolic disorders, including diabetes mellitus (especially type II) and related disorders.
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The invention claimed is: 1. A piperidine derivative of the following formula 1, stereoisomers thereof or pharmaceutically acceptable salts thereof: wherein W is O or N—R h ; R a , R b and R h are each independently H or C 1-3 alkyl; R c is —F or —C 1-3 hyperfluoride alkyl; R d and R e are each independently selected from the group…
Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
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