Method and apparatus for generating focused ultrasonic waves with surface modulation

Patent metadata

Field	Value
Publication number	US-9936969-B2
Application number	US-201214007918-A
Country	US
Kind code	B2
Filing date	Mar 15, 2012
Priority date	Mar 30, 2011
Publication date	Apr 10, 2018
Grant date	Apr 10, 2018

Abstract

The invention relates to a method for generating ultrasonic waves focused on a focal zone ( 5 ) in order to carry out biological lesions, comprising the activation of a plurality of ultrasonic transducer elements ( 3 ).
According to the invention:
a target zone, in which homogenization of the supply of energy of the ultrasonic waves emitted by the ultrasonic transducer elements is desired, is chosen, the focusing effect and the acoustic attenuations of the ultrasonic waves on their path between the target zone and the ultrasonic transducer elements ( 3 ) are determined, the focusing effect and the acoustic attenuations of the ultrasonic waves are compensated, with ultrasonic transducer elements ( 3 ) at least some of which have non-identical emission surfaces such that in the target zone, the supply of energy of the ultrasonic waves emitted by the different ultrasonic transducer elements ( 3 ) is more or less identical.

First claim

The invention claimed is:

1. A method for generating focused ultrasonic waves over a focal zone to produce biological lesions comprising an activation of a plurality of ultrasonic transducer elements distributed over an emission surface to respectively emit a plurality of focused ultrasonic waves in the focal zone, while crossing through propagation media at different acoustic attenuations, the method comprising:
choosing a target zone in which homogenization of contributions of the ultrasonic waves emitted by the plurality of ultrasonic transducer elements during said activation is desired,
calculating a pressure in the target zone by determining a focal effect and acoustic attenuations of the ultrasonic waves on paths of the ultrasonic waves between the target zone and the plurality of ultrasonic transducer elements,
during at least one activation period, compensating the focal effect and the acoustic attenuations of the ultrasonic waves with the plurality of ultrasonic transducer elements, wherein at least some of the plurality of ultrasonic transducer elements have non-identical emission surfaces, and
during said activation period, controlling each of the plurality of ultrasonic transducer elements by excitation signals with substantially identical values, wherein the energy contribution, in the target zone, of the ultrasonic waves emitted by the different ultrasonic transducer elements, during said activation, are substantially identical, to produce biological or tissue lesions;
wherein the plurality of ultrasonic transducer elements are distributed on a concave emission surface.

2. The method according to claim 1 , comprising compensating the focal effects and the acoustic attenuations by assigning each of the plurality of ultrasonic transducer elements a surface weight factor depending on the acoustic attenuation and the focal effect undergone by the ultrasonic waves.

3. The method according to claim 2 , comprising determining the surface weight factor by taking into account a distance between the plurality of ultrasonic transducer elements and a separating zone of the propagation media.

4. The method according to claim 3 , comprising taking into account the distance between the plurality of ultrasonic transducer elements and the separating zone of the propagation media by calculating that distance as a function of a configuration of the propagation media relative to said plurality of ultrasonic transducer elements.

5. The method according to claim 3 , comprising taking into account the distance between the plurality of ultrasonic transducer elements and the separating zone of the propagation media by measuring echoes reflected following sending of a calibration signal by the plurality of ultrasonic transducer elements.

6. The method according to claim 1 , comprising grouping together ultrasonic transducer elements with elementary sizes, thereby forming ultrasonic transducer elements with different emission surfaces configurable based on the encountered acoustic attenuations.

7. The method according to claim 1 , comprising, for the plurality of ultrasonic transducer elements distributed on a concave emission surface with a radius of curvature Rc, calculating a surface area Sn of each ultrasonic transducer element n such that:
Sn =[ S total(1/( Fp ( n )· Z )]

where Fp=power factor,
with Stotal: the sum of the surface areas of the plurality of ultrasonic transducer elements,
Fp ( n )=Max E ( t )/Max E ( n ),

with Max E(t), the maximum value of the energy contribution of the transducer element t situated at a periphery of the emission surface and Max E(n), the maximum value of the energy contribution of the transducer element n in the target zone,
Z: sum of the 1/Fp(n) for all of the transducer elements.

8. A therapeutic apparatus for generating focused ultrasonic waves on a focal zone, the apparatus comprising:
an ultrasonic probe formed by a plurality of ultrasonic transducer elements distributed on an emission surface that is configured to emit a plurality of ultrasonic waves focused in the focal zone, crossing through the propagation media with different acoustic attenuations, wherein the plurality of ultrasonic transducer elements are configured to be excited by control signals coming from a control circuit,
wherein at least some of the plurality of ultrasonic transducer elements are configured to have non-identical emission surfaces,
wherein each of the plurality of ultrasonic transducer elements are controlled, during said activation, by excitation signals with substantially identical values, the plurality of ultrasonic transducer elements being configured and controlled to emit focused ultrasonic waves, and wherein the plurality of ultrasonic transducer elements are further configured and controlled to have substantially identical energy contributions in a target zone, and produce biological or tissue lesions, and
wherein the plurality of ultrasonic transducer elements are distributed on a concave emission surface resulting from a cylindrical geometry created by translating two concave curve segments with a finite length, which are symmetrical relative to a plane of symmetry, the translation being done along a limited length and in a direction perpendicular to a plane containing said concave curve segments.

9. The apparatus according to claim 8 , wherein the ultrasonic transducer elements are distributed according to a concave emission surface that may or may not be truncated.

10. The apparatus according to claim 8 , wherein the ultrasonic transducer elements are distributed in rings or ring segments concentric to each other along a focal axis while having emissions surfaces with different values.

11. The apparatus according to claim 8 , wherein the ultrasonic transducer elements are distributed on a planar surface.

12. The apparatus according to claim 8 , wherein the ultrasonic transducer elements are distributed according to a concave emission surface in the shape of a toroid.

13. The apparatus according to claim 8 , wherein the ultrasonic transducer elements are distributed according to a concave emission surface in the shape of a truncated toroid.

Assignees

• Vincenot Jeremy
• Melodelima David
• Blanc Emmanuel
• Chapelon Jean Yves
• Edap Tms France
• Inst Nat Sante Rech Med

Inventors

• Vincenot Jeremy
• Melodelima David
• Blanc Emmanuel
• Chapelon Jean-Yves

Classifications

• G10K11/32 Primary

  characterised by the shape of the source · CPC title

• A61B17/320068 Primary

  using mechanical vibrations, e.g. ultrasonic (A61B17/22012 takes precedence; dental tooth drilling devices operated by vibration A61C3/03; removing intra-ocular material using mechanical vibrations A61F9/00745) · CPC title