Density phase separation device

Patent metadata

Field	Value
Publication number	US-9933344-B2
Application number	US-201615086903-A
Country	US
Kind code	B2
Filing date	Mar 31, 2016
Priority date	Jul 21, 2008
Publication date	Apr 3, 2018
Grant date	Apr 3, 2018

Abstract

A mechanical separator for separating a fluid sample into first and second phases is disclosed. The mechanical separator includes a float having a first portion and a second portion, a ballast circumferentially disposed about a section of the float, and a deformable bellows defining an open passageway extending between a first end and a second end. The ballast is longitudinally moveable with respect to the float and engaged with the deformable bellows between the first end and the second end. At least a portion of the float is transitionable from a restraint position to a sealed position through the first end of the bellows. The first portion of the float can be positioned within the interior of the deformable bellows in the restraint position, and the first portion of the float can be positioned at an exterior location longitudinally displaced from the deformable bellows in the sealed position.

First claim

The invention claimed is:

1. A mechanical separator comprising:
a float having a first portion and a second portion;
a ballast circumferentially disposed about a portion of the float and longitudinally moveable with respect to the float; and
a deformable bellows having an open first end and an open second end and defining an open passageway extending therebetween, the deformable bellows comprising an exterior surface engaged with a portion of the ballast, and an interior surface releaseably engaged with a portion of the float,
wherein at least a portion of the float is transitionable from a restraint position in which a first portion of the float is positioned within the interior of the deformable bellows and fluid can pass through the passageway to a sealed position in which the first portion of the float extends through the first end of the deformable bellows and fluid cannot pass through the passageway.

2. The mechanical separator of claim 1 , wherein the float has a first density, and the ballast has a second density that is greater than the first density of the float.

3. The mechanical separator of claim 1 , wherein the first portion of the float is positioned at an exterior location longitudinally displaced from the deformable bellows in the sealed position.

4. The mechanical separator of claim 1 , wherein the transition from the restraint position to the sealed position occurs as the float and the ballast exert opposing forces on the deformable bellows.

5. The mechanical separator of claim 1 , wherein the mechanical separator is oriented such that the first portion of the float is positioned below the first end of the deformable bellows in the restraint position, and the first portion of the float is positioned above the first end of the deformable bellows in the sealed position.

6. The mechanical separator of claim 1 , wherein the float and deformable bellows form a liquid impermeable seal in the sealed position.

7. The mechanical separator of claim 2 , wherein the float comprises an engagement protrusion and the deformable bellows comprises a restraint shoulder, the engagement protrusion of the float restrained within the deformable bellows by the restraint shoulder.

8. A separation assembly for enabling separation of a fluid sample into first and second phases, comprising:
a tube, having an open end, an opposing end, and a sidewall extending therebetween;
a closure adapted for a sealing engagement with the open end of the tube, the closure defining a recess; and
a mechanical separator releaseably engaged within the recess, the mechanical separator comprising:
a float having a first portion and a second portion, the float having a first density;
a ballast circumferentially disposed about a portion of the float and longitudinally moveable with respect to the float, the ballast having a second density greater than the first density of the float; and
a deformable bellows having an open first end and an open second end and defining an open passageway extending therebetween, the deformable bellows comprising an exterior surface engaged with a portion of the ballast, and an interior surface releaseably engaged with a portion of the float,
wherein at least a portion of the float is transitionable from a restraint position in which a first portion of the float is positioned within the interior of the deformable bellows and fluid can pass through the passageway to a sealed position in which the first portion of the float extends through the first end of the deformable bellows and fluid cannot pass through the passageway.

9. The separation assembly of claim 8 , wherein the first portion of the float is positioned at an exterior location longitudinally displaced from the deformable bellows in the sealed position.

10. A method of separating a fluid sample into lighter and heavier phases within a tube, comprising the steps of:
subjecting a separation assembly having a fluid sample disposed therein to accelerated rotational forces, the separation assembly comprising:
a tube, having an open end, an opposing end, and a sidewall extending therebetween;
a closure adapted for a sealing engagement with the open end of the tube, the closure defining a recess; and
a mechanical separator releaseably engaged within the recess, the mechanical separator comprising:
a float having a first portion and a second portion;
a ballast circumferentially disposed about a section of the float and longitudinally moveable with respect to the float; and
a deformable bellows engaged with a portion of the sidewall and defining an open passageway extending between a first end of the deformable bellows and a second end of the deformable bellows, the ballast engaged with the deformable bellows between the first end and the second end, and at least a portion of the float transitionable from a restraint position to a sealed position through the first end of the deformable bellows,

disengaging the mechanical separator from the closure;
venting air from within the mechanical separator through the open passageway of the deformable bellows until the mechanical separator is submerged within the fluid;
elongating the deformable bellows to at least partially separate from the sidewall; and
transitioning the float from the restraint position to the sealed position.

11. The method of claim 10 , wherein the lighter and heavier phases of the fluid pass between the sidewall and the deformable bellows during the step of elongating the deformable bellows.

12. The method of claim 10 , wherein the first portion of the float is positioned within the interior of the deformable bellows in the restraint position, and the first portion of the float is positioned at an exterior location longitudinally displaced from the deformable bellows in the sealed position.

13. A separation assembly for enabling separation of a fluid sample into first and second phases, comprising:
a tube, having an open end, an opposing end, and a sidewall extending therebetween;
a closure adapted for a sealing engagement with the open end of the tube; and
a mechanical separator disposed within the tube, the mechanical separator comprising:
a float having a first portion and a second portion, the float having a first density;
a ballast disposed about a portion of the float and longitudinally moveable with respect to the float, the ballast having a second density greater than the first density of the float; and
a deformable bellows interfaced with the float, the bellows having an open first end and an open second end and defining an open passageway extending therebetween, the deformable bellows comprising an exterior surface engaged with a portion of the ballast, and an interior surface releaseably engaged with a portion of the float,
wherein at least a portion of the float is transitionable from a restraint position in which a first portion of the float is positioned within the interior of the deformable bellows and fluid can pass through the passageway to a sealed position in which the first portion of the float extends through the first end of the deformable bellows and fluid cannot pass through the passageway, and
wherein centrifugal force is applied to the separation assembly when filled with fluid components of localized densities ranging from less than the density of the float and greater than the density of the ballast, and wherein sufficient centrifugal forces can seat the bellows onto the float.

Assignees

• Becton Dickinson Co

Inventors

• Newby C Mark
• Battles Christopher A

Classifications

• B01L2400/049

  vacuum · CPC title

• G01N1/4077 Primary

  by other techniques involving separation of suspended solids · CPC title

• B01D17/12

  Auxiliary equipment particularly adapted for use with liquid-separating apparatus, e.g. control circuits · CPC title

• B01L2200/0631

  Purification arrangements, e.g. solid phase extraction [SPE] · CPC title

• B01L2400/0409

  centrifugal forces · CPC title