Oral care compositions and methods

Patent metadata

Field	Value
Publication number	US-9931291-B2
Application number	US-201315106675-A
Country	US
Kind code	B2
Filing date	Dec 20, 2013
Priority date	Dec 20, 2013
Publication date	Apr 3, 2018
Grant date	Apr 3, 2018

Abstract

Provided is an oral care composition comprising a phosphate/acrylate co-polymer, zinc and an orally acceptable carrier and methods of using the same.

First claim

What is claimed is:

1. An oral care composition comprising a phosphate/acrylate co-polymer, zinc, and an orally acceptable carrier, wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and a mixture of 2-hydroxyethyl methacrylate phosphates of Formula 1:

wherein n is 0, 1 or 2.

2. The composition of claim 1 , wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and 2-hydroxyethyl methacrylate phosphates of Formula 1 comprising acrylic acid in a molar percentage of 70-90%; methacrylic acid in a molar percentage of 5-20%, and hydroxyethyl methacrylate phosphates of Formula 1 in a molar percentage of 1-10%.

3. The composition of claim 1 , wherein the phosphate/acrylate co-polymer is a co-polymerized product of a mixture of acrylic acid, methacrylic acid, and 2-hydroxyethyl methacrylate phosphates of Formula 1 comprising acrylic acid in a molar percentage of 80-90% or 85%; methacrylic acid in a molar percentage of 5-15% or 11%, and hydroxyethyl methacrylate phosphates of Formula 1 in a molar percentage of 2-6% or 4%.

4. The composition of claim 1 , wherein the phosphate/acrylate copolymer is a random copolymer having a weight average molecular weight of 10,000 to 500,000, and the phosphate/acrylate copolymer is below its glass transition temperature.

5. The composition of claim 4 , wherein the weight average molecular weight is 10,000 to 200,000 grams per mole, optionally, 10,000 to 40,000, 15,000 to 25,000, or 17,000 to 23,000 grams per mole.

6. The composition of claim 1 , wherein the zinc comprises a soluble zinc compound.

7. The composition of claim 1 , wherein the zinc comprises an insoluble zinc compound.

8. The composition of claim 1 , wherein the zinc comprises a mixture of soluble and insoluble zinc compounds.

9. The composition of claim 1 , wherein the zinc composition comprises ZnO.

10. The composition of claim 1 , wherein the composition comprises 0.1 to 10 weight % ZnO, optionally, 0.1 to 5 weight %, 0.1 to 3 weight %, or 0.1 to 1 weight % ZnO.

11. The composition of claim 1 , wherein the composition comprises zinc citrate.

12. The composition of claim 1 , wherein the composition comprises one or more of water, a thickener, a buffer, a humectant, a surfactant, an abrasive, a sweetener, a flavorant, a visual aid, an anti-caries agent, an anti-bacterial, a whitening agent, a desensitizing agent, a vitamin, a preservative, an enzyme, or a mixture thereof.

13. The composition of claim 12 , wherein the visual aid is a pigment, a dye, or a mixture thereof.

14. The composition of claim 1 , wherein the composition is a mouthwash, toothpaste, tooth gel, tooth powder, non-abrasive gel, mousse, foam, mouth spray, lozenge, oral tablet, dental implement, or pet care product.

15. The composition of claim 1 , comprising:

Ingredient
%

70% Sorbitol
20

99.0%-101.0% Glycerin
20

Water
Q.S.

High Cleaning Silica
10

Abrasive Silica
8.8

Thickening Silica
2.7

Phosphate/acrylate
1-6

co-polymer

Zinc Oxide
0-1

Sodium Lauryl Sulfate
1.5

Sodium Hydroxide
  0-1.2

Sodium carboxymethyl-
1.1

cellulose (CMC)

Flavor
1.0-1.2

Titanium Dioxide
0.75

Propylene Glycol
0.5

Carrageenan Gum
0.48

Sodium Saccharin
0.3

Sodium Fluoride
0.243

16. A method for the treatment and/or inhibition of a chemical stain, plaque, acid erosion, and/or tartar on a dental surface, comprising contacting the dental surface with a composition of claim 1 .

17. A method for the treatment and/or inhibition of gum disease comprising contacting the oral cavity with a composition of claim 1 .

18. A method for the treatment and/or inhibition of halitosis comprising contacting the oral cavity with a composition of claim 1 .

19. A method for the inhibition of biofilm formation on a dental surface comprising contacting the oral cavity with a composition of claim 1 .

20. A method for treating and/or inhibiting bacteria from sticking together and growing into bigger colonies in an oral cavity comprising contacting the oral cavity with a composition of claim 1 .

Assignees

• Colgate Palmolive Co

Inventors

• Prencipe Michael
• Jogun Suzanne
• Morgan Andre Michelle
• Chen Xiang

Classifications

• A61K8/27

  Zinc; Compounds thereof · CPC title

• A61K8/19

  containing inorganic ingredients · CPC title

• A61P1/02

  Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis · CPC title

• A61Q11/00

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title

• A61K8/8152 Primary

  Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers · CPC title