Device and method for determining analyte levels

Patent metadata

Field	Value
Publication number	US-9931067-B2
Application number	US-201615264577-A
Country	US
Kind code	B2
Filing date	Sep 13, 2016
Priority date	Mar 4, 1997
Publication date	Apr 3, 2018
Grant date	Apr 3, 2018

Abstract

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.

First claim

What is claimed is:

1. An implantable sensor system for measuring glucose, the system comprising:
an optical absorbance sensor configured to measure glucose;
sensor electronics operably connected to the sensor; and
a membrane disposed on at least a portion of the sensor, wherein the membrane comprises an outermost domain, wherein the outermost domain is configured to interface with tissue or a biological fluid, wherein the outermost domain comprises a metal portion.

2. The system of claim 1 , wherein the membrane comprises polyurethane.

3. The system of claim 2 , wherein the polyurethane is polyurethaneurea.

4. The system of claim 1 , wherein the membrane comprises an enzyme.

5. The system of claim 4 , wherein the enzyme is glucose oxidase.

6. The system of claim 1 , wherein the metal is platinum.

7. An implantable sensor system for measuring glucose, the system comprising:
an optical absorbance sensor configured to measure glucose;
sensor electronics operably connected to the sensor; and
a membrane disposed on at least a portion of the sensor, wherein the membrane comprises polyurethane, wherein the membrane comprises an outermost domain, wherein the outermost domain is configured to interface with tissue or a biological fluid, wherein the outermost domain comprises a metal portion, wherein the metal portion comprises platinum.

8. An implantable sensor system for measuring glucose, the system comprising:
an optical absorbance sensor configured to measure glucose;
sensor electronics operably connected to the sensor; and
a membrane disposed on at least a portion of the sensor, wherein the membrane comprises polyurethaneurea, wherein the membrane comprises an outermost domain, wherein the outermost domain is configured to interface with tissue or a biological fluid, wherein the outermost domain comprises a metal portion, wherein the metal portion comprises platinum.

Assignees

• Dexcom Inc

Inventors

• Shults Mark C
• Updike Stuart J
• Rhodes Rathbun K
• Gilligan Barbara J
• Tapsak Mark A

Classifications

• A61B5/14532 Primary

  for measuring glucose, e.g. by tissue impedance measurement · CPC title

• A61B5/1455

  using optical sensors, e.g. spectral photometrical oximeters · CPC title

• A61B5/1486

  using enzyme electrodes, e.g. with immobilised oxidase · CPC title

• A61B2562/17

  Comprising radiolucent components · CPC title

• A61B5/1459

  invasive, e.g. introduced into the body by a catheter · CPC title