Nickel ferrite nanoparticle composite and method for preparing same

Patent metadata

Field	Value
Publication number	US-9919932-B2
Application number	US-201214240277-A
Country	US
Kind code	B2
Filing date	Mar 29, 2012
Priority date	Aug 23, 2011
Publication date	Mar 20, 2018
Grant date	Mar 20, 2018

Abstract

The present invention relates to a method for preparing a nickel ferrite nanoparticle composite having an inverse spinel structure obtained using a polyol process, a nickel ferrite nanoparticle composite prepared by the method, and a method for selectively binding, separating or purifying a specific protein using the nickel ferrite nanoparticle composite. The method for preparing a magnetic nanoparticle composite according to the present invention includes a one-step hydrothermal synthesis process, and thereby the magnetic nanoparticle composite can be prepared in a simple and economic manner. Also, the nickel ferrite nanoparticles synthesized by the method of the present invention can be strongly magnetic, and also exist in the form of Ni 2+ in which Ni binds to a specific protein, thereby preventing loss of separability caused by additional oxidation and repeated recycling of the nanoparticles.

First claim

The invention claimed is:

1. A method for preparing a nickel ferrite nanoparticle composite having an inverse spinel structure, comprising:
(1) preparing a mixed solution in which a nickel precursor compound id an iron precursor compound are mixed with a polyol solvent;
(2) adding a pH control agent;
(3) adding a Ni 2+ oxidizing agent and agitating the resulting mixed solution; and
(4) heating the resulting mixed solution to form a nanoparticle composite through reduction of a nickel salt and an iron salt
wherein
said nickel precursor compound is NiCl 2 ,
said iron precursor compound is FeCl 3 ,
said pH control agent is sodium acetate,
said polyol solvent is ethylene glycol (EG), and
said Ni 2+ oxidizing agent is KNO 3 , and

wherein said nickel ferrite nanoparticle composite has a magnetic saturation value of 40 to 50 emu/g.

2. The method of claim 1 , wherein a time required to maintain a reaction temperature of 200° C. or higher is greater than or equal to 8 hours in the heating of the resulting mixed solution to form the nanoparticle composite.

3. The method of claim 1 , further comprising:
washing the reacted nanoparticle composite with a washing solvent and drying the nanoparticle composite in a temperature condition ranging from room temperature to 70° C.

4. The method of claim 3 , wherein the washing solvent is at least one selected from the group consisting of ethanol, acetone, and water.

Assignees

• Jung Gyoo Yeol
• Seo Sang Woo
• Chun Jinyoung
• Lee Jinwoo
• Postech Acad Ind Found

Inventors

• Jung Gyoo Yeol
• Seo Sang Woo
• Chun Jinyoung
• Lee Jinwoo

Classifications

• H01F1/0054

  Coated nanoparticles, e.g. nanoparticles coated with organic surfactant · CPC title

• Y10T428/2982

  Particulate matter [e.g., sphere, flake, etc.] · CPC title

• C01P2004/03

  obtained by SEM · CPC title

• C01P2002/72

  by d-values or two theta-values, e.g. as X-ray diagram · CPC title

• H01F1/36

  in the form of particles {(H01F1/346, H01F1/348 and H01F1/38 take precedence)} · CPC title