Methods and apparatus for removing dissolved gases from fermentation streams
US-9221734-B2 · Dec 29, 2015 · US
US9918938B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9918938-B2 |
| Application number | US-201415024622-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 29, 2014 |
| Priority date | Sep 30, 2013 |
| Publication date | Mar 20, 2018 |
| Grant date | Mar 20, 2018 |
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An object of the present invention is to provide a method for producing selectively a powder particle consisting of the α-form crystal of D-mannitol, using the spray-drying method. It is a method for selective production of powder particles consisting of the α-form crystal of D-mannitol, wherein a D-mannitol solution containing a water-soluble polymer is spray-dried.
Opening claim text (preview).
The invention claimed is: 1. A method for producing selectively an α-form crystal of D-mannitol, comprising a step of performing spray drying of a solution consisting essentially of D-mannitol and a water-soluble polymer, wherein the solution is a mixture solution of a water-soluble organic solvent and water or an aqueous solution, wherein the water-soluble polymer is pectin, carboxyvinyl polymer, brown algae extract, locust bean gum, sodium alginate, hydroxyethyl cellulose, hydroxypropyl cellulose, hypromellose, methyl cellulose, sodium carboxy methylcellulose, xanthan gum, polyethylene oxide, polyethylene glycol, polyvinyl pyrrolidone, polyvinyl alcohol, or polyvinyl pyrrolidone vinylacetate, wherein the content of the water-soluble polymer in the solution is 1% to 60% by weight with respect to D-mannitol. 2. The method according to claim 1 , wherein the water-soluble organic solvent is a C1 to C6 alcohol-based solvent or a C3 to C5 ketone-based solvent. 3. The method according to claim 1 , wherein the water-soluble polymer is polyethylene glycol, polyvinyl pyrrolidone, or polyvinyl alcohol. 4. The method according to claim 1 , wherein the water-soluble polymer is polyethylene glycol. 5. The method according to claim 1 , wherein the molecular weight of the water-soluble polymer is 190 g/mol to 25000 g/mol. 6. The method according to claim 1 , wherein the water-soluble polymer is polyethylene glycol 4000. 7. The method according to claim 1 , wherein the content of the water-soluble polymer in the solution is 2% by weight or more with respect to D-mannitol. 8. The method according to claim 1 , wherein the content of the water-soluble polymer in the solution is 5% by weight or more with respect to D-mannitol. 9. The method according to claim 1 , wherein the content of the water-soluble polymer in the solution is 10% by weight or more with respect to D-mannitol.
by condensation or crystallisation · CPC title
Processes · CPC title
by physical treatment · CPC title
Hexahydroxylic alcohols · CPC title
obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers · CPC title
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