Stable three-phased emulsions

Patent metadata

Field	Value
Publication number	US-9918912-B2
Application number	US-201615000850-A
Country	US
Kind code	B2
Filing date	Jan 19, 2016
Priority date	Mar 11, 2008
Publication date	Mar 20, 2018
Grant date	Mar 20, 2018

Abstract

Disclosed is a water-in-silicone emulsion comprising a discontinuous water phase, a continuous silicone phase, and a silicone polyglucoside containing emulsifier, wherein the discontinuous water phase does not include a salt.

First claim

The invention claimed is:

1. A water-in-silicone emulsion comprising a discontinuous water phase, a continuous silicone phase, and a silicone polyglucoside emulsifier, wherein the discontinuous water phase does not include a salt.

2. The water-in-silicone emulsion of claim 1 , wherein the silicone polyglucoside emulsifier includes an octyl radical and a sugar glucoside.

3. The water-in-silicone emulsion of claim 2 , wherein the sugar glucoside is a 6 carbon monosaccharide ranging from 1-8 monomers in length.

4. The water-in-silicone emulsion of claim 3 , wherein the silicone polyglucoside emulsifier has a molecular weight of at least 450 daltons.

5. The water-in-silicone emulsion of claim 1 , further comprising a co-emulsifier.

6. The water-in-silicone emulsion of claim 5 , wherein the co-emulsifier is a glucolipid.

7. The water-in-silicone emulsion of claim 6 , wherein the glucolipid includes an alkyl chain 8-20 carbons in length and a glucose portion comprising a 5 carbon monosaccharide.

8. The water-in-silicone emulsion of claim 7 , wherein the weight ratio of the silicone polyglucoside emulsifier to the glucolipid co-emulsifier is between 8:1 to 12:1.

9. The water-in-silicone emulsion of claim 1 , wherein the silicone polyglucoside emulsifier is present in an amount of between 3% to 8% by weight based on the total weight of the emulsion.

10. The water-in-silicone emulsion of claim 1 , comprising a viscosity of 20,000 to 30,000 cps at 25° C. as measured on a Brookfield Viscometer using a TC spindle at 2.5 rpm.

11. The water-in-silicone emulsion of claim 1 , wherein the continuous silicone phase comprises a cyclomethicone, an aryl silicone, a dimethicone copolyol, a cyclopentasiloxane, a dimethicone, a short chain siloxanes, or a silicone acrylate, or any combination thereof.

12. The water-in-silicone emulsion of claim 1 , wherein the emulsion is comprised in a topical skin composition.

13. The water-in-silicone emulsion of claim 1 , wherein the emulsion is comprised in a dermatologically acceptable vehicle.

14. A method of delivering a cosmetic or pharmaceutical active ingredient to skin comprising topically applying a composition comprising a cosmetic or pharmaceutical active ingredient and the water-in-silicone emulsion of claim 1 to skin, wherein topical application of the composition delivers the cosmetic or pharmaceutical active ingredient to the skin.

15. The method of claim 14 , wherein the water-in-silicone emulsion comprises a viscosity of 20,000 to 30,000 cps at 25° C. as measured on a Brookfield Viscometer using a TC spindle at 2.5 rpm.

16. The method of claim 14 , wherein the silicone polyglucoside emulsifier is present in an amount of between 3% to 8% by weight based on the total weight of water-in-silicone emulsion.

17. The method of claim 14 , wherein the silicone polyglucoside emulsifier includes an octyl radical and a sugar glucoside.

18. The method of claim 14 , wherein the continuous silicone phase of the water-in-silicone emulsion comprises a cyclomethicone, an aryl silicone, a dimethicone copolyol, a cyclopentasiloxane, a dimethicone, a short chain siloxanes, or a silicone acrylate, or any combination thereof.

19. The method of claim 14 , wherein the water-in-silicone emulsion further comprises a co-emulsifier.

20. The method of claim 19 , wherein the co-emulsifier is a glucolipid.

Assignees

• Mary Kay Inc

Inventors

• Patel Amit

Classifications

• A61P17/00

  Drugs for dermatological disorders · CPC title

• A61K9/0014 Primary

  Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00) · CPC title

• A61K8/585

  Organosilicon compounds · CPC title

• A61K8/064 Primary

  Water-in-oil emulsions, e.g. Water-in-silicone emulsions · CPC title

• A61K8/066

  Multiple emulsions, e.g. water-in-oil-in-water · CPC title