Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
US-9216947-B2 · Dec 22, 2015 · US
Methods for making polymorphs of bromfenac sodium and bromfenac sodium formulations
US9914697B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9914697-B2 |
| Application number | US-201514738004-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 12, 2015 |
| Priority date | Oct 15, 2009 |
| Publication date | Mar 13, 2018 |
| Grant date | Mar 13, 2018 |
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Abstract
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Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
First claim
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What is claimed is: 1. A crystalline form of bromfenac sodium characterized by a powder x-ray diffraction pattern having peaks expressed as 2-theta at about 21.6, 22.4, 12.2, 24.0 and 26.3 degrees. 2. The bromfenac sodium in accordance with claim 1 , wherein the bromfenac sodium is characterized by a powder x-ray diffraction pattern having at least one or more peaks expressed as 2-theta at about 12.4, 14.1, 17.8, 19.6 and 28.1 degrees. 3. The bromfenac sodium in accordance with claim 1 , wherein the bromfenac sodium is free of any other physical forms of bromfenac sodium. 4. A crystalline form of bromfenac sodium characterized by a powder x-ray diffraction pattern in accordance with that shown in FIG. 3 . 5. The bromfenac sodium in accordance with claim 4 , wherein the bromfenac sodium is characterized by an FT-IR spectrum in accordance with that shown in FIG. 4 . 6. A crystalline form of bromfenac sodium characterized by a powder x-ray diffraction pattern characterized by an XRPD d-spacing/% intensity pattern in accordance with that shown in Table B.
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- C07C227/42Primary
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- What does patent US9914697B2 cover?
- Different polymorphs of bromfenac sodium may be prepared and interconverted using crystallization/recrystallization, drying and/or hydration techniques.
- Who is the assignee on this patent?
- Johnson Matthey Plc
- What technology area does this patent fall under?
- Primary CPC classification C07C227/42. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).