Multilayered catheter shaft containing polyvinylidene fluoride polymers

Patent metadata

Field	Value
Publication number	US-9913933-B2
Application number	US-201414214548-A
Country	US
Kind code	B2
Filing date	Mar 14, 2014
Priority date	Mar 15, 2013
Publication date	Mar 13, 2018
Grant date	Mar 13, 2018

Abstract

In various embodiments of the present disclosure, a surgical catheter is provided. The present disclosure provides a catheter shaft that includes a distal portion and a proximal portion. The proximal portion comprises a handle operably connected to the distal portion of the elongated structure. The distal portion three radially positioned polymeric layers. At least two of the layers include chemically dissimilar polymers and at least one of the three layers includes functionalized polyvinylidene fluoride (PVDF).

First claim

What is claimed:

1. A catheter comprising the following:
an elongated structure, wherein the elongated structure has a distal portion, a proximal portion, and a tie band coupled between the distal portion and the proximal portion:
a handle operably connected to a proximal end of the proximal portion of the elongated structure; and
wherein the distal portion comprises a shaft, wherein the shaft comprises three radially positioned polymeric layers that include an inner layer, a middle layer, and an outer layer, wherein at least two of the three layers include chemically dissimilar polymers and the outer layer of the distal portion is formed from a nonpolar polymer, and wherein an outer layer of the tie band is formed from functionalized polyvinylidene fluoride (PVDF) and an outer layer of the proximal portion is formed from a polar polymer.

2. The catheter of claim 1 , wherein the functionalized PVDF comprises polyvinylidene homopolymer grafted with maleic anhydride.

3. The catheter of claim 1 , wherein the functionalized PVDF comprises vinylidene and hexafluoropropylene grafted with maleic anhydride.

4. A catheter shaft configured to be inserted into a patient's body, the catheter shaft comprising the following:
an elongated structure, wherein the elongated structure has a distal portion, a proximal portion, and a tie band disposed between the distal portion and the proximal portion;
a handle operably connected to the proximal end of the proximal portion; and
wherein the distal portion comprises a shaft, wherein the shaft comprises an inner polymeric layer; a middle polymeric layer bonded to the inner polymeric layer; and an outer polymeric layer bonded to the middle polymeric layer, wherein the outer polymeric layer is formed from a hydrophobic polymer, and wherein an outer layer of the tie band is formed from functionalized polyvinylidene fluoride (PVDF) and an outer layer of the proximal portion is formed from a hygroscopic polymer.

5. The catheter shaft of claim 4 , wherein the inner layer of the distal portion comprises PVDF homopolymer, the middle layer of the distal portion comprises PVDF copolymer, and the outer layer of the distal portion comprises the functionalized PVDF.

6. The catheter shaft of claim 4 , wherein the inner layer of the distal portion comprises the PVDF homopolymer, the middle layer of the distal portion comprises the functionalized PVDF, and the outer layer of the distal portion comprises the PVDF homopolymer.

7. The catheter shaft of claim 4 , wherein the inner layer of the distal portion comprises the PVDF copolymer, the middle layer of the distal portion comprises the functionalized PVDF, and the outer layer of the distal portion comprises the PVDF copolymer.

8. The catheter shaft of claim 7 , wherein the PVDF copolymer comprises a copolymer of vinylidene fluoride with hexafluoropropylene.

9. The catheter shaft of claim 4 , wherein the inner polymeric layer of the distal portion comprises the functionalized PVDF, the middle polymeric layer of the distal portion comprises a polyamide, and the outer polymeric layer of the distal portion comprises the functionalized PVDF.

10. The catheter shaft of claim 9 , wherein the polyamide is selected from the group consisting of nylon 11 , nylon 12 , and combinations thereof.

11. The catheter shaft of claim 4 , wherein the inner polymeric layer of the distal portion comprises nylon, the middle polymeric layer of the distal portion comprises the functionalized PVDF, and the outer polymeric layer of the distal portion comprises the PVDF copolymer.

12. The catheter shaft of claim 4 , wherein the inner polymeric layer of the distal portion comprises the PVDF homopolymer, the middle polymeric layer of the distal portion comprises the functionalized PVDF, and the outer polymeric layer of the distal portion comprises nylon.

13. The catheter shaft of claim 12 , wherein the nylon is selected from the group consisting of nylon 11 , nylon 12 , and combinations thereof.

14. The catheter shaft of claim 4 , further comprising a metal wire braid layer proximate to an interface of the inner and middle polymeric layers of the distal portion.

15. The catheter shaft according to claim 4 , further comprising a metal wire braid layer proximate to a junction of the middle and outer polymeric layers of the distal portion.

16. A catheter shaft, comprising the following:
a proximal segment;
a handle operatively connected to the proximal segment;
a transitional segment; and
a distal segment;
wherein each of the proximal segment, the transitional segment, and the distal segment has an inner polymeric layer, a middle polymeric layer, and an outer polymeric layer, wherein the outer polymeric layer of the transitional segment is formed of functionalized polyvinylidene fluoride (PVDF), wherein at least one of the inner and middle polymeric layers in the distal segment is formed of functionalized PVDF, and the outer polymeric layer of the distal segment is formed of a nonpolar polymer and the outer polymeric layer of the proximal segment is formed of a polar polymer.

17. The catheter shaft of claim 16 , wherein the inner polymeric layer of each segment is formed of the functionalized PVDF.

18. The catheter shaft of claim 16 , wherein the middle polymeric layer of each segment is formed from a polymer selected from the group consisting of a poly (ether block amide), a polyamide, and combinations thereof.

19. The catheter shaft of claim 16 , further comprising a reinforcing spring extending along the inner polymeric layer from the proximal segment and through a portion of the distal segment.

20. The catheter shaft according to claim 19 , further comprising a shrink tube placed around a distal end of the reinforcing spring configured to alleviate stress rise therefrom.

21. The catheter shaft of claim 16 , wherein the middle polymer layer is formed of different polymers between the proximal segment, the transitional segment, and the distal segment.

22. The catheter shaft of claim 21 , wherein a flexibility of the middle polymeric layer increases from the proximal segment to the distal segment.

23. The catheter shaft of claim 22 , wherein each one of the inner polymeric layer, the middle polymeric layer, and the outer polymeric layer of the proximal segment are formed from at least one type of polyamide.

24. The catheter shaft of claim 23 , wherein the inner polymer layer of the transitional segment and the distal segment are formed from the at least one type of polyamide.

25. The catheter shaft of claim 24 , further comprising a tie band between the proximal segment and the transitional segment, wherein the tie band comprises an inner polymeric layer formed of the at least one polyamide and a middle polymeric layer and outer polymeric layer formed of the functionalized PVDF.

26. The catheter shaft of claim 25 , wherein the transitional segment and the distal segment each has an inner polymeric layer formed of the at least one type of polyamide, a middle polymeric layer formed of a functionalized PVDF, and an outer polymeric layer formed of a polymer selected from the group consisting of PVDF homopolymer and PVDF copolymer.

Assignees

• St Jude Medical Cardiology Div Inc

Inventors

• Guo Xiaoping
• Johnson David P

Classifications

• A61M25/0053

  having a variable stiffness along the longitudinal axis, e.g. by varying the pitch of the coil or braid · CPC title

• A61L29/085

  Macromolecular materials · CPC title

• A61L2400/10

  Materials for lubricating medical devices · CPC title

• A61L29/126 Primary

  having a macromolecular matrix · CPC title

• A61M25/0054

  with regions for increasing flexibility · CPC title