Implantable prosthesis with radiopaque particles and method of making same

Patent metadata

Field	Value
Publication number	US-9907682-B2
Application number	US-201615356930-A
Country	US
Kind code	B2
Filing date	Nov 21, 2016
Priority date	Jun 26, 2012
Publication date	Mar 6, 2018
Grant date	Mar 6, 2018

Abstract

An implantable prosthesis can comprise a strut having a lumen, radiopaque particles within the lumen, and a polymer binder. The polymer binder retains the radiopaque particles within the lumen. The strut may have side holes through which a therapeutic agent may pass and through which the radiopaque particles are incapable of passing. The polymer binder may be absent or optional. The radiopaque particles can have sizes that prevent them from escaping out of the lumen through the side holes. The radiopaque particles placed within the lumen can improve visualization of the prosthesis during an implantation procedure.

First claim

What is claimed is:

1. An implantable prosthesis comprising:
a strut having a metal wall that defines a lumen within the strut, the metal wall made of a base material and is not formed from sintered particles of the base material; and
radiopaque particles within the lumen, the radiopaque particles sintered onto the metal wall.

2. The implantable prosthesis of claim 1 , wherein the metal wall forms an exterior surface of the strut.

3. The implantable prosthesis of claim 2 , wherein a plurality of holes are formed through the metal wall.

4. The implantable prosthesis of claim 3 , further comprising a therapeutic agent disposed within the lumen and capable of passing through the holes after the prosthesis is implanted in a patient.

5. The implantable prosthesis of claim 4 , wherein the therapeutic agent is disposed within gaps between the radiopaque particles.

6. The implantable prosthesis of claim 5 , wherein the radiopaque particles are sintered together.

7. The implantable prosthesis of claim 1 , wherein the base material of the metal wall comprises a material selected from the group consisting of 316L stainless steel, CoNi MP35N, CoCr L-605, and FePtCr.

8. The implantable prosthesis of claim 1 , wherein the radiopaque particles comprise a material selected from the group consisting of gold, Au/Pt/Zn 85/10/5 alloy, and Au/Ag/Pt/Zn 73/12/0.5/15 alloy.

9. The implantable prosthesis of claim 1 , wherein each of the radiopaque particles has a diameter from 10 nanometers to 25 micrometers.

10. The implantable prosthesis of claim 9 , wherein the lumen has a diameter from 0.01 mm to 0.25 mm.

11. The implantable prosthesis of claim 1 , further comprising a plurality of undulating rings, wherein the rings are connected together, and the strut forms at least a portion of the plurality of the undulating rings.

12. The implantable prosthesis of claim 1 , further comprising:
a second strut having a metal wall that defines a lumen centrally located within the second strut; and
radiopaque particles located within the lumen of the second strut and sintered onto the metal wall of the second strut.

13. The implantable prosthesis of claim 1 , wherein the strut is a hollow wire.

Assignees

• Abbott Cardiovascular Systems Inc

Inventors

• Pacetti Stephen

Classifications

• A61L31/16

  Biologically active materials, e.g. therapeutic substances {(A61L31/047 takes precedence)} · CPC title

• A61F2250/0098

  radio-opaque, e.g. radio-opaque markers · CPC title

• A61F2250/0068

  the pharmaceutical product being in a reservoir · CPC title

• A61F2002/91566

  connected trough to trough · CPC title

• A61L31/18

  Materials at least partially X-ray or laser opaque · CPC title