Material decomposition technique using x-ray phase contrast imaging system

Patent metadata

Field	Value
Publication number	US-9907524-B2
Application number	US-201514874748-A
Country	US
Kind code	B2
Filing date	Oct 5, 2015
Priority date	Dec 21, 2012
Publication date	Mar 6, 2018
Grant date	Mar 6, 2018

Abstract

A phase contrast x-ray imaging system generates an absorption image and a phase shift image of an object under study. The absorption image represents a measurement of the imaged object's attenuation of radiographic energy, and the phase shift image represents a measurement of the imaged object's phase shifting of the radiographic waves passing through the object. The two images may be used to improve soft tissue discrimination in radiographic imaging.

First claim

What is claimed is:

1. A method comprising:
radiographically scanning an object containing first type material and second type material using a phase contrast imaging (PCI) system;
generating a plurality of radiographic images in response to the step of scanning, including generating a first image of the object that represents levels of absorption of radiographic radiation by the object and generating a second image that represents phase shifts of the radiographic radiation caused by the object; and
calculating a proportional amount of the first type material in the object and calculating a proportional amount of the second type material in the object based on both a function of the absorption of radiographic radiation by the object per unit of length of the object and of the phase shifts of radiographic radiation caused by the object per unit of length of the object.

2. The method of claim 1 , further comprising setting an x-ray source in the imaging system to emit radiographic energy having substantially one energy level.

3. The method of claim 1 , wherein the step of scanning comprises firing an x-ray source emitting broadband radiographic energy aimed at the object.

4. The method of claim 3 , wherein the step of scanning comprises moving a grating of the PCI imaging system through a plurality of discrete steps.

5. The method of claim 4 , wherein the step of scanning further comprises stepping the grating of the PCI imaging system through a full cycle of an interference pattern generated by the PCI imaging system.

6. The method of claim 5 , wherein the step of generating the first image of the object includes averaging intensity levels of the radiographic energy passing through the object at the plurality of discrete steps.

7. The method of claim 1 , wherein the first type material consists of glandular tissue and the second type material consists of adipose tissue, and the method further comprises calculating a proportional amount of the glandular tissue in the object and a proportional amount of the adipose tissue in the object.

8. A phase contrast imaging system comprising:
a radiographic energy source;
a flat panel digital detector;
an object to be imaged positioned between the radiographic energy source and the detector, the object containing first type material and second type material; and
means for calculating a proportional amount of a first type of material in the object and a proportional amount of a second type of material in the object based on both a function of the absorption of radiographic energy by the object per unit of length of the object and of the phase shifts of radiographic energy caused by the object per unit of length of the object,
wherein the source and detector are configured to radiographically expose the object containing the first type material and the second type material to produce a plurality of images of the exposed object, and
wherein a first one of the produced images comprises image data representing the object's attenuation of the radiographic energy and a second one of the produced images comprises image data representing a phase shift of the radiographic energy passing through the object.

9. The system of claim 8 , further comprising three gratings configured to produce the plurality of images of the exposed object, wherein the object is positioned between two of the gratings.

10. The system of claim 9 , wherein the radiographic energy source is a broadband x-ray source.

11. The system of claim 9 , wherein the radiographic energy source is configured to emit radiographic energy having substantially one energy level.

12. The system of claim 10 , wherein the system is configured to move one of the gratings a plurality of discrete steps while radiographically exposing the object.

13. The system of claim 12 , wherein said one of the gratings comprises a plurality of equally sized slots and wherein the system is configured to move said one of the gratings the plurality of discrete steps totaling a distance of one slot width.

14. The system of claim 13 , wherein the image data representing the object's attenuation of the radiographic energy is based on an average attenuation by the object of radiographic energy at the discrete steps.

15. The system of claim 8 , wherein the first type of material consists of glandular tissue and the second type of material consists of adipose tissue.

Assignees

• Carestream Health Inc

Inventors

• Baturin Pavlo
• Shafer Mark E

Classifications

• A61B6/4291

  the detector being combined with a grid or grating · CPC title

• A61B6/481

  involving the use of contrast agents · CPC title

• A61B6/484 Primary

  involving phase contrast X-ray imaging · CPC title