Apparatus for processing biological material

Patent metadata

Field	Value
Publication number	US-9901935-B2
Application number	US-201414551375-A
Country	US
Kind code	B2
Filing date	Nov 24, 2014
Priority date	Sep 26, 2005
Publication date	Feb 27, 2018
Grant date	Feb 27, 2018

Abstract

A gripper unit for handling a vessel for receiving biological material is proposed, inter alia. The vessel has a lid which can assume an open position and a closed position. The gripper unit comprises a gripper for gripping and releasing the vessel, and a lid holder, for holding a lid in a defined position in relation to the vessel. The defined position is an open position of the lid.

First claim

The invention claimed is:

1. An apparatus for processing biological material, comprising:
a centrifuge having a rotatable centrifuge rotor with at least one vessel holder comprising a holding member for holding a vessel for biological material, at least one lid receptor for holding a lid attached to the vessel, and a positioning counter-element shaped for engaging with a positioning element, and
a gripper with a lid holder attached thereto, wherein the gripper is capable of being used for transferring a vessel from a first holding position of the vessel holder to a second holding position of the vessel holder,

wherein the at least one lid receptor is shaped to allow access to the lid by the lid holder, wherein the access to the lid of the lid holder comprises mechanical contacting of the lid by the lid holder, wherein the lid receptor has an opening which allows access by the lid holder to the lid, wherein the lid receptor is constructed so as to fix the lid in a secure position during centrifuging, and
wherein the lid holder is adapted to make contact with the lid through the opening and provide a stop for it, so that during removal of the vessel from the vessel holder or during insertion of the vessel therein the lid can be removed from the lid receptor or placed therein while retaining the position defined by the lid holder.

2. The apparatus for processing biological material according to claim 1 , wherein the gripper further comprises a positioning element for positioning an angular position or a deflection angle of the vessel holder by interaction with the positioning counter-element.

3. An apparatus for processing biological material according to claim 2 , wherein the centrifuge rotor is rotatable about a rotor axis, said apparatus further comprising a drive for the centrifuge rotor,
wherein the positioning element is not co-rotatable with the rotor, and
wherein the positioning counter-element is co-rotatable with the rotor.

4. An apparatus for processing biological material according to claim 2 , further comprising a suspension means which can be suspended in the centrifuge rotor and into which the vessel holder is insertable,
wherein the suspension means comprises a first stop for the pivoting movement of the vessel holder insertable thereinto,
wherein the positioning element is suitable for securing the vessel holder at a deflection angle at the stop by interaction with the positioning counter-element of the vessel holder,
wherein the centrifuge rotor is rotatable about a rotor axis, which is suitable for the pivotal mounting of the vessel holder.

5. An apparatus for processing biological material of claim 1 , further comprising a vessel,
wherein the vessel comprises at least one vessel part of increased recognisability, and wherein said apparatus comprises
a radiation source for irradiating a registration area in the vessel holder, wherein the registration area is associated with the vessel part of increased recognisability;
a sensor for measuring the intensity of radiation coming from the registration area;
an evaluating unit which is equipped to register the presence or absence of the vessel by running a comparison between the intensity measured and a defined threshold.

6. The apparatus according to claim 5 , wherein the sensor is movable.

7. An apparatus for processing biological material according to claim 1 , further comprising:
a sensor unit with an ultrasound source and an ultrasound sensor; and
an evaluating unit for determining, as a function of sensor data of the ultrasound sensor, the state of opening of the vessel, and for determining, as a function of sensor data of the ultrasound sensor and with the vessel open, the presence of a substance in the vessel.

8. The apparatus according to claim 7 , wherein the sensor unit is movable and further comprises:
a radiation sensor, and
a positioner for positioning the sensor unit in relation to the vessel as a function of sensor data of the radiation sensor.

9. An apparatus for processing biological material according to claim 1 , further comprising
a container station for keeping a supply of vessels;
a marking on the container station, which contains information as to the nature of the vessels; and
a radiation sensor for reading the marking.

10. The apparatus according to claim 9 , further comprising a radiation source for irradiating the marking.

Assignees

• Qiagen Gmbh

Inventors

• Schaefer Andreas
• Voit Thomas
• Tschopp Walter
• Geiger Adrian
• Zbinden Markus
• Hibbing Harald
• Karl Andreas
• Eigemeier Frank
• Behrmann Volker
• Kopp Dietmar
• Schmiede Andreas

Classifications

• G01N2035/00801

  Holders for sample carriers, e.g. trays, caroussel, racks · CPC title

• G01V8/10

  Detecting, e.g. by using light barriers (by reflection from the object G01S17/00) · CPC title

• G01N35/0099

  comprising robots or similar manipulators (robots per se B25J) · CPC title

• B04B2011/046

  Loading, unloading, manipulating sample containers · CPC title

• B01L2300/043

  Hinged closures · CPC title