Monitoring apparatus for monitoring an ablation procedure

Patent metadata

Field	Value
Publication number	US-9901321-B2
Application number	US-201013142299-A
Country	US
Kind code	B2
Filing date	Jan 8, 2010
Priority date	Jan 14, 2009
Publication date	Feb 27, 2018
Grant date	Feb 27, 2018

Abstract

The present invention relates to a monitoring apparatus ( 101 ) for monitoring an ablation procedure. The monitoring apparatus ( 101 ) comprises an ultrasound signal providing unit for providing an ultrasound signal that depends on received echo series of an object ( 4 ) that is ablated. The monitoring apparatus ( 101 ) further comprises an ablation depth determination unit ( 103 ) for determining an ablation depth from the provided ultrasound signal. The ablation depth can be determined directly from the ultrasound signal and is an important parameter while performing an ablation procedure. For example, it can be used for determining the progress of ablation within the object ( 4 ) and for determining when the ablation has reached a desired progression.

First claim

The invention claimed is:

1. A monitoring apparatus for monitoring an ablation procedure applied to an object, the monitoring apparatus comprising:
an ultrasound signal providing unit structurally configured to provide an ultrasound signal produced by sending ultrasound pulses out to the object, to receive dynamic echo series after the ultrasound pulses have been reflected by the object, and to generate the ultrasound signal depending on the received dynamic echo series; and
an ablation depth determination unit structurally configured to determine an ablation depth being defined by a boundary of a lesion within the object from the provided ultrasound signal.

2. The monitoring apparatus as defined in claim 1 ,
wherein the provided ultrasound signal represents ultrasound reflection properties of the object at different depths and at different times, and
wherein the ablation depth determination unit is structurally configured to determine a discontinuity of the ultrasound signal and to determine the ablation depth as the depth of the ultrasound signal at which the discontinuity occurs.

3. The monitoring apparatus as defined in claim 1 ,
wherein the provided ultrasound signal represents ultrasound reflection properties of the object at different depths and at different times, and
wherein the ablation depth determination unit is structurally configured to:
correct the ultrasound signal for a theimal expansion of the object caused by the ablation procedure, and
determine the ablation depth and an ablation time as the depth and the time of temporally subsequent signal values of the corrected ultrasound signal, which correspond to the same depth and which are not similar with respect to a predefined similarity measure.

4. The monitoring apparatus as defined in claim 1 ,
wherein the provided ultrasound signal represents ultrasound reflection properties of the object at different depths and at different times,
wherein the ablation depth determination unit is structurally configured to:
correct the ultrasound signal for a thermal expansion of the object caused by the ablation procedure,
determine stretches comprised of temporally subsequent signal values of the corrected ultrasound signal, which correspond to the same depth and which are similar with respect to a similarity measure, and
determine the ablation depth and an ablation time as the depth and the time at which the length of the stretches is below a predefined threshold.

5. The monitoring apparatus as defined in claim 1 ,
wherein the provided ultrasound signal represents ultrasound reflection properties of the object at different depths and at different times, and
wherein the ablation depth determination unit is structurally configured to:
correct the ultrasound signal for a thermal expansion of the object caused by the ablation procedure,
determine, for differmt depth regions and at the different times, a cross correlation of temporally subsequent signal values of the same depth region, and
determine an ablation depth and an ablation time depending on the cross correlation of the temporally subsequent signals determined for the different depth regions and at the different times.

6. The monitoring apparatus as defined in claim 5 ,
wherein the ablation depth determination unit is structurally configured to determine, for different depth regions and at the different times, a shift value depending on the determined cross correlation and to determine an ablation depth and an ablation time depending on the determined shift values, and
wherein a shift value is indicative of a shift between temporally subsequent signals within a depth region.

7. The monitoring apparatus as defined in claim 1 , further comprising an ablation unit structurally configured to ablate the object.

8. The monitoring apparatus as defined in claim 7 , further comprising a control unit structurally configured to control the ablation unit depending on the determined ablation depth.

9. The monitoring apparatus as defined in claim 1 ,
wherein the object is a wall,
wherein the apparatus is structurally configured to determine the thickness of the wall and repeatedly the ablation depth, and
wherein the ablation depth determination unit is structurally configured to determine repeatedly a degree of transmurality of ablation from the determined thickness and the determined ablation depth.

10. The monitoring apparatus as defined in claim 9 , wherein the apparatus is structurally configured to terminate an ablation procedure, if a predetermined degree of transmurality of ablation has been reached.

11. The monitoring apparatus as defined in claim 1 , wherein the object is a wall and wherein the ablation depth determination unit is structurally configured to determine the position of a front surface and a back surface of the wall from the ultrasound signal.

12. The monitoring apparatus as defined in claim 11 , wherein the ablation depth determination unit is structurally configured to determine the thickness of the wall from the determined positions of the front surface and the back surface of the wall.

13. The monitoring apparatus as defined in claim 1 ,
wherein the ultrasound signal providing unit includes an ultrasound unit structurally configured to send ultrasound pulses out to the object, to receive dynamic echo series after the ultrasound pulses have been sent out to the object, and to generate an ultrasound signal depending on the received dynamic echo series, and
wherein the monitoring apparatus further comprises a catheter, wherein the ultrasound unit is located within the catheter.

14. A monitoring method for monitoring an ablation procedure applied to an object, the monitoring method comprising the steps of:
providing an ultrasound signal produced by
sending ultrasound pulses out to the object,
receiving dynamic echo series after the ultrasound pulses have been reflected by the object, and
generating the ultrasound signal depending on the received dynamic echo series; and

determining an ablation depth being defined by a boundary of a lesion within the object from the generated ultrasound signal.

15. A non-transitory computer medium for monitoring an ablation procedure applied to an object, the non-transitory computer medium comprising program code for causing a monitoring apparatus as defined in claim 1 to carry out the following steps when the computer program is run on a computer controlling the monitoring apparatus:
providing an ultrasound signal produced by
sending ultrasound pulses out to the object,
receiving dynamic echo series after the ultrasound pulses have been reflected by the object,
generating the ultrasound signal depending on the received dynamic echo series; and

determining an ablation depth being defined by a boundary of a lesion within the object from the generated ultrasound signal.

Assignees

• Harks Erik
• Deladi Szabolcs
• Suijver Jan Frederik
• Jankovic Ladislav
• Shi Yan
• Rensen Wouter Harry Jacinth
• Barley Maya
• Van Der Vaart Nijs Cornelis
• Koninklijke Philips Nv

Inventors

• Harks Erik
• Deladi Szabolcs
• Suijver Jan Frederik
• Jankovic Ladislav
• Shi Yan
• Rensen Wouter Harry Jacinth
• Barley Maya
• Van Der Vaart Nijs Cornelis

Classifications

• A61B8/0858 Primary

  involving measuring tissue layers, e.g. skin, interfaces · CPC title

• A61B18/20

  using laser · CPC title

• A61B18/1492

  having a flexible, catheter-like structure, e.g. for heart ablation (A61B18/1477 takes precedence) · CPC title

• A61B2218/002

  Irrigation · CPC title

• A61B2018/00738

  Depth, e.g. depth of ablation · CPC title