Focused ultrasound system with optimized monitoring of cavitation
US-11872085-B2 · Jan 16, 2024 · US
US9901319B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9901319-B2 |
| Application number | US-201515326053-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 16, 2015 |
| Priority date | Nov 18, 2014 |
| Publication date | Feb 27, 2018 |
| Grant date | Feb 27, 2018 |
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The invention relates to peripheral equalization during a mammography X-ray examination. High contrast tissue pixel values are removed from the background estimate by finding the minimum intensity values of the pixel located in the neighborhood, which have approximately the same distance to the skin line. Thus, high attenuating pixel values may be removed from the estimate and replaced by lower attenuating tissue pixel values. After a minimum filtration, a conventional peripheral equalization is performed. This may result in less overshoots and intensity values for higher attenuating structures in the peripheral region may become more consistent with intensity values for higher attenuating structures in the fully compressed region.
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The invention claimed is: 1. An examination apparatus for examination of an object of interest, comprising: a processor: a storage readable by the processor and storing image data of an image of the object of interest, the image data comprising object data and non-object data; and a non-transitory computer-readable medium storing instructions executable by the processor to perform a method including: segmenting the object data from the non-object data; determining a line, which is an iso-contour and extends at a constant distance from a boundary of the object of interest or which extends along a constant thickness of the object of interest; generating a minimum filtered image by performing a minimum filtering of the object data along the iso-contour, thereby replacing a higher intensity value of a first pixel positioned on the iso-contour by a lower intensity value of a second pixel positioned on the iso-contour and in the neighborhood of the first pixel; performing a peripheral equalization of the object data by: determining a background data estimate by low-pass filtering the minimum-filtered image; subtracting the background data estimate from the image data; adding a desired homogenous background attenuation image to the image data. 2. The examination apparatus according to claim 1 , wherein the method further includes, before the minimum filtering: pre-blurring of the object data using a low-pass filter. 3. The examination apparatus according to claim 1 , wherein the iso-contour is determined by evaluation of spectral data. 4. The examination apparatus according to claim 1 , wherein the iso-contour is determined by identifying the boundary of the object of interest from the non-object data, the image data or the object data. 5. The examination apparatus according to claim 1 , wherein the minimum filtering of the object data along the iso-contour comprises a selection of the first pixel, a determination of the intensity value of the first pixel, a determination of the intensity values of a predetermined number of pixel positioned on the iso-contour and adjacent to the first pixel, and a replacement of the intensity value of the first pixel by the lowest intensity value of the predetermined number of adjacent pixel. 6. The examination apparatus according to claim 1 , wherein the peripheral equalization of the object data comprises a low-pass filtering. 7. The examination apparatus according to claim 1 , wherein the examination apparatus is one of a two-dimensional mammography examination apparatus and a tomosynthesis examination apparatus. 8. A non-transitory computer readable medium storing instructions, which, when being executed by a processing unit, instruct the processing unit to: access image data of an image of the object of interest, the image data comprising object data and non-object data; segment the object data from the non-object data; determine a line, which is an iso-contour and extends at a constant distance from a boundary of the object of interest or which extends along a constant thickness of the object of interest; generate a minimum filtered image by performing a minimum filtering of the object data along the iso-contour, thereby replacing a higher intensity value of a first pixel positioned on the iso-contour by a lower intensity value of a second pixel positioned on the iso-contour and in the neighborhood of the first pixel; and perform a peripheral equalization of the object data by: determining a background data estimate by low-pass filtering the minimum-filtered image; subtracting the background data estimate from the image data; and adding a desired homogenous background attenuation image to the image data. 9. The non-transitory computer readable medium according to claim 8 , wherein the processing unit is adapted for performing, before the minimum filtering: pre-blurring of the object data using a low-pass filter. 10. The non-transitory computer readable medium according to claim 8 , wherein the iso-contour is determined by evaluation of spectral data. 11. The non-transitory computer readable medium according to claim 8 , wherein the iso-contour is determined by identifying the boundary of the object of interest from the non-object data, the image data or the object data. 12. The non-transitory computer readable medium according to claim 8 , wherein the minimum filtering of the object data along the iso-contour comprises a selection of the first pixel, a determination of the intensity value of the first pixel, a determination of the intensity values of a predetermined number of pixel positioned on the iso-contour and adjacent to the first pixel, and a replacement of the intensity value of the first pixel by the lowest intensity value of the predetermined number of adjacent pixel. 13. The non-transitory computer readable medium according to claim 8 , wherein the peripheral equalization of the object data comprises a low-pass filtering. 14. A method of examining an object of interest, comprising: acquiring image data of an image of the object of interest, the image data comprising object data and non-object data; segmenting the object data from the non-object data; determining a line, which is an iso-contour and extends at a constant distance from a boundary of the object of interest or which extends along a constant thickness of the object of interest; generating a minimum filtered image by performing a minimum filtering of the object data along the iso-contour, thereby replacing a higher intensity value of a first pixel positioned on the iso-contour by a lower intensity value of a second pixel positioned on the iso-contour and in the neighborhood of the first pixel; performing a peripheral equalization of the object data by: determining a background data estimate by low-pass filtering the minimum-filtered image; subtracting the background data estimate from the image data; adding a desired homogenous background attenuation image to the image data. 15. An examination apparatus for examination of an object of interest, the apparatus comprising: a storage device configured to provide image data of an image of the object of interest, the image data comprising object data and non-object data; at least one electronic processor programmed to: segment the object data from the non-object data; determine an iso-contour extending at a constant distance from a boundary of the object of interest or which extends along a constant thickness of the object of interest; generate a minimum filtered image by replacing a higher intensity value of a first pixel positioned on the iso-contour by a lower intensity value of a second pixel positioned on the iso-contour and in the neighborhood of the first pixel; perform a peripheral equalization of the object data by: determining a background data estimate by low-pass filtering the minimum-filtered image; subtracting the background data estimate from the image data; adding a desired homogenous background attenuation image to the image data. 16. The examination apparatus according to claim 15 , wherein the at least one electronic processor is further programmed to: pre-blur of the object data using a low-pass filter before generating the minimum filtered image. 17. The examination apparatus according to claim 15 , wherein the at least one electronic processor is further programmed to: determine the iso-contour by evaluating spectral data of the object of interest. 18. The examination apparatus according to claim 15 , wherein the at least one elec
involving processing of medical diagnostic data · CPC title
for computer-aided diagnosis, e.g. based on medical expert systems · CPC title
Mammography; Breast · CPC title
X-ray image · CPC title
for diagnosis of breast, i.e. mammography · CPC title
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