Cellulose ethers esterified with dicarboxylic acid

US9890221B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9890221-B2
Application numberUS-201414777838-A
CountryUS
Kind codeB2
Filing dateMay 7, 2014
Priority dateMay 14, 2013
Publication dateFeb 13, 2018
Grant dateFeb 13, 2018

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

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Esterified cellulose ethers comprising groups of formula —C(O)—CHR′—CHR″—COOA, wherein, R′ and R″ are hydrogen or (—S)m(—R 1 )n-R 2 , wherein R 1 is a hydrocarbon group having 1 to 4 carbon atoms, R 2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A is hydrogen or a cation, with the proviso that in each group CHR′—CHR″ one of R′ and R″ is hydrogen and the other one is (—S)m(—R 1 )n-R 2 , are useful as excipients for maintaining the concentration of poorly water-soluble drugs in aqueous liquids at supersaturation levels.

First claim

Opening claim text (preview).

The invention claimed is: 1. An esterified cellulose ether comprising groups of formula —C(O)—CHR′—CHR″—COOA, wherein one of R′ or R″ is hydrogen and the other of R′ of R″ is (—S) m (—R 1 ) n —R 2 , wherein R 1 is a hydrocarbon group having 1 to 4 carbon atoms, R 2 is an optionally substituted 5- or 6-membered cyclic group, m is 1, n is 0 or 1, and A is hydrogen or a cation. 2. The esterified cellulose ether of claim 1 wherein R 1 is CH 2 . 3. The esterified cellulose ether of claim 1 wherein R 2 is non-substituted 5- or 6-membered cyclic group. 4. The esterified cellulose ether of claim 1 wherein n=0. 5. The esterified cellulose ether of claim 1 wherein R 2 is cyclohexyl or phenyl. 6. The esterified cellulose ether of claim 1 being an esterified hydroxyalkyl methylcellulose.

Assignees

Inventors

Classifications

  • Cellulose; Derivatives thereof · CPC title

  • with organic macromolecular compounds · CPC title

  • having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin · CPC title

  • Sulfur, selenium, or tellurium compounds, e.g. thiols · CPC title

  • C08B13/00Primary

    Preparation of cellulose ether-esters · CPC title

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What does patent US9890221B2 cover?
Esterified cellulose ethers comprising groups of formula —C(O)—CHR′—CHR″—COOA, wherein, R′ and R″ are hydrogen or (—S)m(—R 1 )n-R 2 , wherein R 1 is a hydrocarbon group having 1 to 4 carbon atoms, R 2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A is hydrogen or a cation, with the proviso that in each group CHR′—CHR″ one of R′ and R″ i…
Who is the assignee on this patent?
Dow Global Technologies Llc, The Regents Of The Univ Of Minnesota, Univ Minnesota
What technology area does this patent fall under?
Primary CPC classification C08B13/00. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).