Cellulose resin and method for producing the same
US-9512238-B2 · Dec 6, 2016 · US
US9890221B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9890221-B2 |
| Application number | US-201414777838-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 7, 2014 |
| Priority date | May 14, 2013 |
| Publication date | Feb 13, 2018 |
| Grant date | Feb 13, 2018 |
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Esterified cellulose ethers comprising groups of formula —C(O)—CHR′—CHR″—COOA, wherein, R′ and R″ are hydrogen or (—S)m(—R 1 )n-R 2 , wherein R 1 is a hydrocarbon group having 1 to 4 carbon atoms, R 2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A is hydrogen or a cation, with the proviso that in each group CHR′—CHR″ one of R′ and R″ is hydrogen and the other one is (—S)m(—R 1 )n-R 2 , are useful as excipients for maintaining the concentration of poorly water-soluble drugs in aqueous liquids at supersaturation levels.
Opening claim text (preview).
The invention claimed is: 1. An esterified cellulose ether comprising groups of formula —C(O)—CHR′—CHR″—COOA, wherein one of R′ or R″ is hydrogen and the other of R′ of R″ is (—S) m (—R 1 ) n —R 2 , wherein R 1 is a hydrocarbon group having 1 to 4 carbon atoms, R 2 is an optionally substituted 5- or 6-membered cyclic group, m is 1, n is 0 or 1, and A is hydrogen or a cation. 2. The esterified cellulose ether of claim 1 wherein R 1 is CH 2 . 3. The esterified cellulose ether of claim 1 wherein R 2 is non-substituted 5- or 6-membered cyclic group. 4. The esterified cellulose ether of claim 1 wherein n=0. 5. The esterified cellulose ether of claim 1 wherein R 2 is cyclohexyl or phenyl. 6. The esterified cellulose ether of claim 1 being an esterified hydroxyalkyl methylcellulose.
Cellulose; Derivatives thereof · CPC title
with organic macromolecular compounds · CPC title
having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin · CPC title
Sulfur, selenium, or tellurium compounds, e.g. thiols · CPC title
Preparation of cellulose ether-esters · CPC title
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