Circulation apparatus and method for controlling same

Patent metadata

Field	Value
Publication number	US-9889245-B2
Application number	US-201514868484-A
Country	US
Kind code	B2
Filing date	Sep 29, 2015
Priority date	Apr 1, 2013
Publication date	Feb 13, 2018
Grant date	Feb 13, 2018

Abstract

A highly reliable circulation apparatus promptly detects an abnormal state of a status value related to blood flowing in a circulation circuit with no particular operation performed. As an extracorporeal circulation mode starts, a user operates a pump first and waits until a flow rate is stabilized. Then, when the flow rate is stabilized, a predetermined value is added to or subtracted from the stabilized flow rate so as to set two threshold values which regulate an upper end and a lower end of a permissible state range. Then, it is monitored whether or not the flow rate is within the permissible state range regulated by the threshold values, and when the flow rate deviates from the permissible state range, an alarm is issued for notification.

First claim

What is claimed is:

1. A circulation apparatus which causes blood of a patient to circulate outside a human body by using a circulation circuit, the apparatus comprising:
a detector for detecting a status value related to blood while being provided on a flow path through which blood flows in the circulation circuit; and
a processor configured to:
determine whether or not a stable state in which the status value exhibits transition within a range set in advance is achieved after the circulation circuit starts blood circulation;
set two threshold values which respectively regulate an upper end and a lower end of a permissible state range based on the status value in the stable state when it is determined that the stable state is achieved;
monitor whether or not the status value is within the permissible state range which is regulated by the two threshold values, after the stable state is achieved;
issue an alarm when deviation of the status value from the permissible state range is detected;
determine, after it is determined that the stable state is achieved, whether or not an acquired differential value of the status value with respect to a time axis, for a predetermined number of consecutive acquired differential values, is above a threshold value range set in advance;
issue the alarm when it is determined that the acquired differential value of the status value with respect to the time axis, for the predetermined number of consecutive acquired differential values, is above the threshold value range set in advance;
determine, after it is determined that the stable state is achieved, whether or not the acquired differential value of the status value with respect to the time axis, for the predetermined number of consecutive acquired differential values, is below the threshold value range set in advance; and
issue the alarm when it is determined that the acquired differential value of the status value with respect to the time axis, for the predetermined number of consecutive acquired differential values, is below the threshold value range set in advance.

2. The circulation apparatus according to claim 1 ,
wherein the processor is further configured to detect volume of blood flowing inside the circulation circuit per unit time.

3. The circulation apparatus according to claim 1 ,
wherein the processor is further configured to detect pressure related to blood flowing inside the circulation circuit.

4. The circulation apparatus according to claim 1 ,
wherein the processor is further configured to detect a temperature of blood flowing inside the circulation circuit.

5. The circulation apparatus according to claim 1 ,
wherein the processor is further configured to detect volume of blood flowing inside the circulation circuit per unit time, or pressure related to blood flowing inside the circulation circuit, or a temperature of blood flowing inside the circulation circuit.

6. A method of controlling a circulation apparatus which causes blood of a patient to circulate outside a human body using a circulation circuit, the method comprising:
a detecting step of detecting a status value related to blood while being performed on a flow path through which blood flows in the circulation circuit;
a determining step of determining whether or not a stable state in which the status value exhibits transition within a range set in advance is achieved after the circulation circuit starts blood circulation;
a setting step of setting two threshold values which respectively regulate an upper end and a lower end of a permissible state range based on the status value in the stable state when it is determined that the stable state is achieved through the determining step;
a monitoring step of monitoring whether or not the status value is within the permissible state range which is regulated by the two threshold values, after the stable state is achieved; and
a warning step of issuing an alarm when it is detected that the status value deviates from the permissible state range through the monitoring step;
a second monitoring step of determining, after it is determined that the stable state is achieved, whether or not an acquired differential value of the status value with respect to a time axis, for a predetermined number of consecutive acquired differential values, is above a threshold value range set in advance;
a second warning step of issuing the alarm when it is determined that the acquired differential value of the status value with respect to the time axis, for the predetermined number of consecutive acquired differential values, is above the threshold value range set in advance;
a third monitoring step of determining, after it is determined that the stable state is achieved, whether or not the acquired differential value of the status value with respect to the time axis, for the predetermined number of consecutive acquired differential values, is below the threshold value range set in advance; and
a third warning step of issuing the alarm when it is determined that the acquired differential value of the status value with respect to the time axis, for the predetermined number of consecutive acquired differential values, is below the threshold value range set in advance.

7. The method according to claim 6 ,
wherein the detecting step detects volume of blood flowing inside the circulation circuit per unit time.

8. The method according to claim 6 ,
wherein the detecting step detects pressure related to blood flowing inside the circulation circuit.

9. The method according to claim 6 ,
wherein the detecting step detects a temperature of blood flowing inside the circulation circuit.

10. The method according to claim 6 ,
wherein the detecting step detects volume of blood flowing inside the circulation circuit per unit time, or pressure related to blood flowing inside the circulation circuit, or a temperature of blood flowing inside the circulation circuit.

11. A non-transitory, tangible computer readable recording medium storing a program which, when executed by a computer, causes the computer to control a circulation apparatus which causes blood of a patient to circulate outside a human body using a circulation circuit by performing the following steps:
a detecting step of detecting a status value related to blood while being performed on a flow path through which blood flows in the circulation circuit;
a determining step of determining whether or not a stable state in which the status value exhibits transition within a range set in advance is achieved after the circulation circuit starts blood circulation;
a setting step of setting two threshold values which respectively regulate an upper end and a lower end of a permissible state range based on the status value in the stable state when it is determined that the stable state is achieved through the determining step;
a monitoring step of monitoring whether or not the status value is within the permissible state range which is regulated by the two threshold values, after the stable state is achieved; and
a warning step of issuing an alarm when it is detected that the status value deviates from the permissible state range through the monitoring step;
a second monitoring step of determining, after it is determined that the stable state is achieved, whether or not an acquired differential value of the status value with respect to a time axis, for a predetermined number of consecutive acquired differential values, is above a threshold value range set in advance;
a second warning step of issuing the alarm when it is determined that the acquired differential value of the status value with respect to the time axis, for the predetermined number

Assignees

• Terumo Corp

Inventors

• Utsugida Tomoki
• Hanai Ryosuke

Classifications

• A61M2205/3355

  Controlling downstream pump pressure · CPC title

• A61M2205/3606

  cooled · CPC title

• A61M2205/3368

  Temperature · CPC title

• A61M1/1698

  Blood oxygenators with or without heat-exchangers (intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00) · CPC title

• A61M1/3667

  with assisted venous return · CPC title