Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US-2017348214-A1 · Dec 7, 2017 · US
Prostamide-containing intraocular implant
US9889142B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9889142-B2 |
| Application number | US-201615075922-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 21, 2016 |
| Priority date | Mar 15, 2013 |
| Publication date | Feb 13, 2018 |
| Grant date | Feb 13, 2018 |
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Abstract
Official abstract text for this publication.
Prostamide-containing biodegradable intraocular implants, prostamide compounds, prostamide-containing pharmaceutical compositions, and methods for making and using such implants and compositions for the immediate and sustained reduction of intraocular pressure and treatment of glaucoma in an eye of a patient are described.
First claim
Opening claim text (preview).
What is claimed is: 1. A method for reducing intraocular pressure in a patient, comprising administering a biodegradable implant comprising a biodegradable polymer material, hexadecan-1-ol, and about 8% by weight of a compound having the formula wherein the compound and the hexadecan-1-ol are associated with the biodegradable polymer material, and wherein the biodegradable polymer material comprises i) a poly(D,L-lactide) having an ester end group and an inherent viscosity of 0.25-0.35 dl/g, ii) a poly(D,L-lactide) having an acid end group and an inherent viscosity of 0.16-0.24 dl/g, and iii) a poly(D,L-lactide-co-glycolide) having an ester end group, an inherent viscosity of 0.16-0.24 dl/g, and a D,L-lactide:glycolide molar ratio of about 75:25, wherein the inherent viscosity of each poly(D,L-lactide) and poly(D,L-lactide-co-glycolide) polymer as given above is measured for a 0.1% solution of the polymer in chloroform at 25° C. 2. The method of claim 1 , wherein the patient has elevated intraocular pressure, ocular hypertension, or glaucoma. 3. The method of claim 2 , wherein the intraocular implant reduces the intraocular pressure in the eye by at least 30%, relative to the intraocular pressure in the eye before receiving the implant, for 3-5 months or more following placement in the eye.
Assignees
Inventors
Classifications
Antiglaucoma agents or miotics · CPC title
Ophthalmic agents · CPC title
- A61K31/559Primary
having heterocyclic rings containing hetero atoms other than oxygen · CPC title
Materials at least partially resorbable by the body · CPC title
with organic macromolecular compounds · CPC title
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Frequently asked questions
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- What does patent US9889142B2 cover?
- Prostamide-containing biodegradable intraocular implants, prostamide compounds, prostamide-containing pharmaceutical compositions, and methods for making and using such implants and compositions for the immediate and sustained reduction of intraocular pressure and treatment of glaucoma in an eye of a patient are described.
- Who is the assignee on this patent?
- Allergan Inc
- What technology area does this patent fall under?
- Primary CPC classification A61K31/559. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).