Novel nicotine dna vaccines
US-2015017201-A1 · Jan 15, 2015 · US
Methods of rational nicotine hapten design and uses thereof
US9884114B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9884114-B2 |
| Application number | US-201615189930-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 22, 2016 |
| Priority date | Jun 23, 2015 |
| Publication date | Feb 6, 2018 |
| Grant date | Feb 6, 2018 |
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Abstract
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Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction.
First claim
Opening claim text (preview).
We claim: 1. A nicotine hapten comprising a structure selected from the group consisting of 2. A nicotine hapten conjugate comprising a nicotine hapten and an immunogenic carrier linked to the nicotine hapten, wherein the conjugate is an immunogen capable of eliciting production of antibodies having an affinity index greater than 0.02 and less than or equal to 1, wherein the nicotine hapten has a structure selected from the group consisting of: 3. The conjugate of claim 2 , wherein the nicotine hapten has the structure: 4. A therapeutic composition capable of eliciting an immune response to nicotine, the composition comprising at least one nicotine hapten conjugate of claim 2 . 5. The composition of claim 4 , further comprising an adjuvant bound to the nicotine hapten conjugate. 6. A method for eliciting an immune response in a subject, the method comprising administering to the subject the composition of claim 4 .
Assignees
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Classifications
- A61K39/385Primary
Haptens or antigens, bound to carriers · CPC title
containing three or more hetero rings · CPC title
Physics · mapped topic
the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines · CPC title
Physics · mapped topic
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Frequently asked questions
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- What does patent US9884114B2 cover?
- Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction.
- Who is the assignee on this patent?
- Univ Arizona State
- What technology area does this patent fall under?
- Primary CPC classification A61K39/385. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).