Disinfecting wound dressing and process for preparing such

Patent metadata

Field	Value
Publication number	US-9883974-B2
Application number	US-201013518666-A
Country	US
Kind code	B2
Filing date	Dec 28, 2010
Priority date	Dec 28, 2009
Publication date	Feb 6, 2018
Grant date	Feb 6, 2018

Abstract

A process for preparing a disinfecting wound dressing for the protection of wounds, such as burn wounds, ulcers and cuts, the process comprising the steps of providing a yarn-based substrate, subjecting a surface of the substrate to a plasma environment, thereby providing non-leaching and biocidal features to the substrate surface by exposing the substrate surface to an antimicrobial active compound reaction.

First claim

The invention claimed is:

1. A disinfecting wound dressing for the protection of wounds, such as burn wounds, ulcers and cuts, comprising:
a yarn-based substrate layer composed of filaments of “x”, “v”, “w”, “y”, hexachannel, or tetrachannel form, having non-leaching and biocidal features, provided by exposing said substrate layer to a reaction with an antimicrobial active compound comprising
subjecting the surface of the substrate to an environment resulting in either chain-transfer activation, radiation activation, photochemical activation, and/or chemical activation;
a wound contact layer preventing the wound dressing from sticking to a wound, wherein said contact layer is combined with or identical to said substrate layer and wherein said combined substrate and contact layers also comprises absorbing and water evaporating properties.

2. The wound dressing according to claim 1 , further including a top layer provided with a structure preventing micro-organisms from entering the wound dressing, and having non-leaching and biocidal features.

3. The wound dressing according to claim 1 , wherein a top layer contains a layer of nanofibres.

4. The wound dressing according to claim 1 , wherein the antimicrobial active compound includes a quaternary ammonium moiety.

5. The wound dressing according to claim 4 , wherein the antimicrobial active compound is selected from the group consisting of triclosan, triclcarban, chlorhexidine, chloroxylenol, chitosan acetate, zinc sulphadiazine, and sodium dichloroisocyanurate.

6. A disinfecting wound dressing for the protection of wounds, such as burn wounds, ulcers and cuts, comprising:
a yarn-based substrate layer composed of filaments of “x”, “v”, “w”, “y”, hexachannel, or tetrachannel form, having non-leaching and biocidal features, provided by exposing said substrate layer to a reaction with an antimicrobial active compound comprising subjecting the surface of the substrate to an environment resulting in either chain-transfer activation, radiation activation, photochemical activation, and/or chemical activation;
a wound contact layer preventing substantial penetration of cream or ointment in the wound dressing and having a feature of non-sticking to a dried cream or ointment in the case cream or ointment is applied, wherein said contact layer may be combined with or identical to the substrate layer, and wherein said combined substrate and contact layer also comprises absorbing and water evaporating properties.

7. The wound dressing according to claim 6 , further including a top layer provided with a structure preventing micro-organisms from entering the wound dressing, and having non-leaching and biocidal features.

8. The wound dressing according to claim 6 , wherein the top layer contains a layer of nanofibres.

9. The wound dressing according to claim 6 , wherein the antimicrobial active compound includes a quaternary ammonium moiety.

10. The wound dressing according to claim 9 , wherein the antimicrobial active compound is selected from the group consisting of triclosan, triclcarban, chlorhexidine, chloroxylenol, chitosan acetate, zinc sulphadiazine, and sodium dichloroisocyanurate.

Assignees

• Simor Marcel
• Schilt Andre
• Alkema Duurt Pieter Willem
• Huijser Timo
• TNO

Inventors

• Simor Marcel
• Schilt Andre
• Alkema Duurt Pieter Willem
• Huijser Timo

Classifications

• A61P31/00

  Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics · CPC title

• A61F2013/00217

  not adhering to the wound · CPC title

• A61F2013/00238

  characterised by way of knitting or weaving · CPC title

• D06M10/025

  Corona discharge or low temperature plasma · CPC title

• A61L15/46

  Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria · CPC title