DNA-PK inhibitors for treatment of cancer

US9878993B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9878993-B2
Application numberUS-201615159378-A
CountryUS
Kind codeB2
Filing dateMay 19, 2016
Priority dateApr 24, 2012
Publication dateJan 30, 2018
Grant dateJan 30, 2018

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  1. Title

    What the patent document calls the invention.

  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

    The legal scope of protection — read this for what is actually claimed.

  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of potentiating a therapeutic regimen for the treatment of breast cancer, colorectal cancer, gastric-esophageal cancer, fibrosarcoma, glioblastoma, hepatocellular cancer, head and neck cancer, melanoma, lung cancer, pancreatic cancer or prostate cancer in a patient comprising the step of administering to said patient an effective amount of a compound selected from the group consisting of:

Assignees

Inventors

Classifications

  • Antineoplastic agents · CPC title

  • specific for leukemia · CPC title

  • Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

  • not condensed and containing further heterocyclic rings, e.g. timolol · CPC title

  • Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim · CPC title

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Frequently asked questions

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What does patent US9878993B2 cover?
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
Who is the assignee on this patent?
Vertex Pharma
What technology area does this patent fall under?
Primary CPC classification A61K31/506. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jan 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 11 related publications on this page (citations in our corpus or others sharing the same primary CPC).