Method and magnetic resonance apparatus for quality control in planning radiotherapy of a patient

Patent metadata

Field	Value
Publication number	US-9878178-B2
Application number	US-201615215740-A
Country	US
Kind code	B2
Filing date	Jul 21, 2016
Priority date	Jul 21, 2015
Publication date	Jan 30, 2018
Grant date	Jan 30, 2018

Abstract

In a quality control method and computer for planning radiotherapy of patient, magnetic resonance (MR) image data, acquired from a planning volume of a patient, are provided to a computer and are used in the computer to generate a first electron density map of the planning volume. A second electron density map is generated using the first electron density map, wherein a value of electron density for a bone region in the planning volume is reduced compared to the first electron density map. First and second radiation dose distributions in the planning volume are respectively determined from the radiotherapy plan and the first electron density map, and the radiotherapy plan and the second electron density map. These distributions are compared in order to generate output information.

First claim

I claim as my invention:

1. A quality control method for planning radiotherapy of a patient, comprising:
providing a computer with magnetic resonance image data acquired from a planning volume of a patient;
in said computer, using the magnetic resonance data to generate a first electron density map of said planning volume, said first electron density map having a first value of the electron density for at least one bone region in the planning volume;
in said computer, using said first electron density map to calculate a second electron density map, said second electron density map having a second value of the electron density for said at least one bone region, that is reduced with respect to said first value of said electron density for said at least one bone region;
providing said computer with an electronic designation of a radiotherapy plan for implementing radiotherapy of a target volume situated in said planning volume;
in said computer, using said radiotherapy plan and said first electron density map to determine a first radiation dose distribution in the planning volume;
in said computer, using said radiotherapy plan and said second electron density map to determine a second radiation dose distribution in the planning volume;
in said computer, comparing said first radiation dose distribution with said second radiation dose distribution to obtain a comparison result; and
in said computer, using said comparison result to generate output information related to implementation of said radiotherapy plan, and making an electronic signal representing said output information available from said computer as an output.

2. A method as claimed in claim 1 comprising, in said computer, generating a final radiation therapy plan using only said output information and said magnetic resonance image data acquired from said planning volume.

3. A method as claimed in claim 1 comprising, dependent on said output information, acquiring further planning image data from the patient using a different imaging modality than magnetic resonance imaging, and merging said further planning image data into planning of said radiotherapy of the patient.

4. A method as claimed in claim 1 comprising calculating said second electron density map in said computer by threshold value segmenting of said first electron density map to identify said at least one bone region in said first electron density map.

5. A method as claimed in claim 1 comprising reducing said second value of said electron density in said second electron density map relative to said first value of said electron density of said at least one bone region in said first electron density map by setting said second value of the electron density in said at least one bone region to a value of electron density of soft tissue.

6. A method as claimed in claim 1 wherein said first electron density map comprises at least one air region in said planning volume that has a third electron density value, and calculating said second electron density map using said first electron density map by increasing a fourth value of electron density in said air region relative to said third value.

7. A method as claimed in claim 6 comprising increasing said fourth value of the electron density in said second electron density map relative to said third value of the electron density in said first electron density map by setting the fourth value of the electron density in said at least one air region to a value of electron density of soft tissue.

8. A method as claimed in claim 1 comprising using said output information in said computer to generate a final radiotherapy plan specifically adapted to the patient.

9. A method as claimed in claim 1 comprising providing an electronic designation of a standard radiotherapy plan to said computer, as said radiotherapy plan.

10. A method as claimed in claim 1 comprising comparing said first radiation dose distribution with said second radiation dose distribution in said computer by comparing at least one first radiation dose value in said first radiation dose distribution with at least one second radiation dose value in said second radiation dose distribution.

11. A method as claimed in claim 1 comprising comparing said first radiation dose distribution with said second radiation dose distribution in said computer by comparing a characteristic of a first radiation dose-volume histogram of said first radiation dose distribution with a characteristic of a second radiation dose-volume histogram of said second radiation dose distribution.

12. A method as claimed in claim 1 comprising from said comparison result, calculating a quantitative value in said computer that characterizes the comparison of the first radiation dose distribution with the second radiation dose distribution, and including said quantitative value in said output information.

13. A radiotherapy planning computer, comprising:
a processor having an input that receives magnetic resonance image data acquired from a planning volume of a patient;
said processor being configured to use the magnetic resonance data to generate a first electron density map of said planning volume, said first electron density map having a first value of the electron density for at least one bone region in the planning volume;
said processor being configured to use said first electron density map to calculate a second electron density map, said second electron density map having a second value of the electron density for said at least one bone region, that is reduced with respect to said first value of said electron density for said at least one bone region;
said input of said processor also receiving an electronic designation of a radiotherapy plan for implementing radiotherapy of a target volume situated in said planning volume;
said processor being configured to use said radiotherapy plan and said first electron density map to determine a first radiation dose distribution in the planning volume;
said processor being configured to use said radiotherapy plan and said second electron density map to determine a second radiation dose distribution in the planning volume;
said processor being configured to compare said first radiation dose distribution with said second radiation dose distribution to obtain a comparison result; and
said processor being configured to use said comparison result to generate output information related to implementation of said radiotherapy plan, and making an electronic signal representing said output information available from said computer as an output.

14. A magnetic resonance apparatus comprising:
a magnetic resonance data acquisition scanner;
a computer configured to operate the magnetic resonance data acquisition scanner to acquire magnetic resonance image data acquired from a planning volume of a patient;
said computer being configured to use the magnetic resonance data to generate a first electron density map of said planning volume, said first electron density map having a first value of the electron density for at least one bone region in the planning volume;
said being configured to use said first electron density map to calculate a second electron density map, said second electron density map having a second value of the electron density for said at least one bone region, that is reduced with respect to said first value of said electron density for said at least one bone region;
said computer being configured to receive with an electronic designation of a radiotherapy plan for implementing radiotherapy of a target volume situated in said planning volume;
said computer being configured to use said radio

Assignees

• Siemens Healthcare Gmbh

Inventors

• Schweizer Bernd

Classifications

• A61N5/1039 Primary

  using functional images, e.g. PET or MRI · CPC title

• G01R33/5608

  Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels (image data processing or generation, in general G06T) · CPC title

• G01R33/4808

  Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT] · CPC title