Methods and compositions for treating aged skin

Patent metadata

Field	Value
Publication number	US-9877916-B2
Application number	US-201715599094-A
Country	US
Kind code	B2
Filing date	May 18, 2017
Priority date	Jan 21, 2016
Publication date	Jan 30, 2018
Grant date	Jan 30, 2018

Abstract

A composition comprising an extract from damaged plant parts from the Moringaceae genus, at least one oligopeptide, at least one extract from the Laminaria genus, and whey protein and a method for stimulating collagen synthesis in skin cells.

First claim

The invention claimed is:

1. A method for stimulating collagen synthesis in skin cells by applying a composition comprising an extract from live, damaged plant parts from the Moringa genus which release myosinase enzyme in an amount sufficient to cause the extract to contain Moringa isothiocyanates, in combination with a mixture of an oligopeptide, an extract from the Laminaria genus, and whey protein.

2. The method of claim 1 wherein the composition is applied in the form of a skin cream or lotion.

3. The method of claim 1 wherein the composition is applied once or twice per day.

4. The method of claim 1 wherein the extract from Moringa genus has a Moringa isothiocyanate concentration ranging from 0.5 to 3.5% by weight of the total Moringa extract.

5. The method of claim 1 wherein the oligopeptide is selected from an acetylated peptide, a palmitoylated peptide, a myristolated peptide, or combinations thereof.

6. The method of claim 5 wherein the extract from the Moringa genus is Moringa oleifera , the oligopeptide is an acetylated peptide which is Acetyl hexapeptide-8, and the extract from Laminaria genus is Laminaria digitata.

7. The method of claim 6 wherein the composition is in the form of an emulsion.

8. The method of claim 1 wherein the oligopeptide is an acetylated, or palmitoylated peptide.

9. The method of claim 8 wherein the oligopeptide is a hexapeptide.

10. The method of claim 9 wherein the hexapeptide is an acetylated hexapeptide.

11. The method of claim 10 wherein the acetylated hexapeptide is acetyl hexapeptide-8.

12. The method of claim 1 wherein the Laminaria genus is Laminaria digitata.

13. The method of claim 1 wherein the stimulation of collagen synthesis in skin cells is demonstrated on fibroblasts tested in vitro.

14. The method of claim 13 wherein the stimulation in collagen synthesis in skin cells is a dose/response increase in collagen synthesis.

15. A method for stimulating collagen synthesis in skin cells by applying an aqueous based composition comprising an extract from live, damaged plant parts from the Moringa genus which release myosinase enzyme in an amount sufficient to cause the extract to contain from about 0.5 to 3.5% by weight of the total extract of Moringa isothiocyanates; at least one oligopeptide; an extract from the Laminaria genus, and whey protein.

16. The method of claim 15 wherein the oligopeptide is an acetylated peptide, a myristoylated peptide, a palmitoylated peptide, or combinations thereof.

17. The method of claim 16 wherein the extract from the Laminaria genus is Laminaria digitata.

18. The method of claim 15 wherein the aqueous based composition is an emulsion.

Assignees

• Elc Man Llc

Inventors

• Pernodet Nadine
• Corallo Krystle
• Layman Dawn
• Collins Donald

Classifications

• A61K8/9789

  Magnoliopsida [dicotyledons] · CPC title

• A61K8/97 Primary

  from algae, fungi, lichens or plants; from derivatives thereof · CPC title

• A61K8/64 Primary

  Proteins; Peptides; Derivatives or degradation products thereof · CPC title

• A61Q1/10

  for eyes, e.g. eyeliner, mascara · CPC title

• A61Q19/10

  Washing or bathing preparations · CPC title