Mixing device for homogenization of cell suspensions

Patent metadata

Field	Value
Publication number	US-9873858-B2
Application number	US-201514721468-A
Country	US
Kind code	B2
Filing date	May 26, 2015
Priority date	Jun 2, 2014
Publication date	Jan 23, 2018
Grant date	Jan 23, 2018

Abstract

The invention is directed to a homogenization device for cell suspensions, comprising a first rotating magnet; a shaft on which a propeller mixer is attached which rotates around the longitudinal axis of the shaft and is movable in lateral direction of the axis of the shaft; the propeller mixer being provided with at least two propeller blades of which at least one is provided with a second magnet; wherein the propeller mixer is rotated by magnetic interaction of the second magnet with the first rotating magnet.

First claim

What is claimed is:

1. A homogenization device for cell suspensions, comprising:
a first rotating magnet;
a shaft on which a propeller mixer is attached, which rotates around the longitudinal axis of the shaft and is movable in a lateral direction of the axis of the shaft;
wherein the propeller mixer is provided with at least two propeller blades of which at least one is provided with a second magnet; wherein the propeller mixer is rotated by magnetic interaction of the second magnet with the first rotating magnet.

2. The homogenization device according to claim 1 , characterized in that the propeller mixer is provided with two propeller blades, each blade having a single magnet.

3. The homogenization device according to claim 2 , characterized in that the magnet in each propeller blades is oriented with alternating poles.

4. The homogenization device according to claim 1 , characterized in that the propeller mixer is moved in the direction of the axis of the shaft by adjusting a rotational speed of the first rotating magnet.

5. The homogenization device according to claim 1 , characterized in that the shaft and the first rotating magnet are aligned coaxial.

6. The homogenization device according to claim 1 , characterized in that the propeller mixer has a diameter perpendicular to the longitudinal axis of the shaft of 2-50 mm.

7. The homogenization device according to claim 1 , characterized in that at least one mixing vessel having a cover and a bottom is provided and wherein the shaft is attached to the cover of the mixing vessel and the first rotating magnet is located adjacent to the cover of the mixing vessel.

8. The homogenization device according to claim 1 , characterized in that at least one mixing vessel having a cover and a bottom is provided and wherein the shaft is attached to the bottom of the mixing vessel and the first rotating magnet is located adjacent to the bottom of the mixing vessel.

9. The homogenization device according to claim 1 , characterized in that the second magnet is embedded in the propeller blades.

10. The homogenization device according to claim 1 , wherein the propeller blades which are inclined to the axis of rotation, and configured to enable the movement of the propeller on the shaft.

11. The homogenization device according to claim 1 , wherein the propeller blades are cone- or peak-shaped perpendicular to the plate of rotation with an angle of 1° to 180°.

12. The homogenization device according to claim 1 , wherein the propeller blades are configured to mix small volumes of liquid in vessels having a pointed or round bottom.

13. The homogenization device according to claim 1 , wherein opposing propeller blades are tilted against each other, enhancing movement of the propeller on the shaft.

14. The homogenization device according to claim 1 , wherein the propeller mixer and the shaft have no mechanical connection.

15. A homogenization device for cell suspensions, comprising:
a first rotating magnet;
a shaft on which a propeller is attached, which rotates around the longitudinal axis of the shaft and is movable in a direction of the axis of the shaft;
wherein the propeller is provided with at least two propeller blades of which at least one is provided with a second magnet; wherein the propeller is rotated by magnetic interaction of the second magnet with the first rotating magnet.

Assignees

• Miltenyi Biotec Gmbh
• Miltenyi Biotec Gmbh

Inventors

• Boddenberg Jan
• Miltenyi Stefan
• Fritzsch Frederik

Classifications

• B01F7/00225

  Operations & Transport · mapped topic

• B01F7/00183

  Operations & Transport · mapped topic

• B01F7/162

  Operations & Transport · mapped topic

• B01F13/0827

  Operations & Transport · mapped topic

• B01F13/1022

  Operations & Transport · mapped topic