Intraocular device for dual incisions

Patent metadata

Field	Value
Publication number	US-9872799-B2
Application number	US-201615207329-A
Country	US
Kind code	B2
Filing date	Jul 11, 2016
Priority date	Apr 24, 2012
Publication date	Jan 23, 2018
Grant date	Jan 23, 2018

Abstract

A microsurgical device and methods of its use can be used for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. A dual-blade device can be used for cutting the trabecular meshwork (“TM”) in the eye. The device tip provides entry into the Schlemm's canal via its size (i.e., for example, 0.2-0.3 mm width) and configuration where a ramp elevates the TM away from the outer wall of the Schlemm's canal and guides the TM to first and second lateral elements for creating first and second incisions through the TM. The dimensions and configuration of the blade is such that an entire strip of TM is removed without leaving TM leaflets behind and without causing collateral damage to adjacent tissues.

First claim

What is claimed is:

1. A method for incising a trabecular meshwork, the method comprising:
providing a device for incising the trabecular meshwork, the device comprising:
a platform for elevating a portion of the trabecular meshwork away from an outer wall of a Schlemm's canal, the platform comprising a tip at a distal side of the platform and a planar ramp extending from the distal side to a proximal side of the platform, opposite the distal side of the platform, wherein the ramp increases from a distal thickness at the distal side to a proximal thickness, greater than the distal thickness, at the proximal side; and
first and second lateral elements for creating first and second incisions through the trabecular meshwork, the first and second lateral elements (i) being separated by a gap having a width and (ii) extending from the proximal side of the platform;

inserting the tip into a Schlemm's canal of a patient;
advancing the ramp between the trabecular meshwork and an outer wall of the Schlemm's canal such that (i) a portion of the trabecular meshwork on the planar ramp is elevated away from the outer wall of the Schlemm's canal without cutting the portion of the trabecular meshwork from surrounding portions of the trabecular meshwork and (ii) the portion is guided to the first and second lateral elements; and
creating first and second incisions through the trabecular meshwork with each of the first and second lateral elements while the portion of the trabecular meshwork remains elevated away from the outer wall of the Schlemm's canal so a strip of the trabecular meshwork has a width between the first and second incisions corresponding to the width of the gap.

2. The method of claim 1 , wherein creating the first and second incisions comprises creating only the first and second incisions.

3. The method of claim 1 , wherein the strip between the first and second incisions remains intact after creating the first and second incisions.

4. The method of claim 1 , further comprising excising the strip from the trabecular meshwork after the strip has reached a desired length.

5. The method of claim 1 , wherein creating the first and second incisions is performed without ablation or burning of the trabecular meshwork.

6. The method of claim 1 , wherein creating the first and second incisions is performed while the portion of the trabecular meshwork is stretched to be elevated away from the outer wall of the Schlemm's canal.

7. The method of claim 1 , wherein creating the first and second incisions is performed while the portion of the trabecular meshwork is under tension that is greater than the tension of the trabecular meshwork in a natural state.

8. The method of claim 1 , wherein the first lateral element creates the first incision along a first portion of the trabecular meshwork that is guided along a first side of the platform and the second lateral element creates the second incision along a second portion of the trabecular meshwork that is guided along a second side of the platform.

9. A method for incising a trabecular meshwork, the method comprising:
inserting a tip at a distal side of a platform into a Schlemm's canal of a patient;
advancing a ramp of the platform between the trabecular meshwork and an outer wall of the Schlemm's canal such that (i) a portion of the trabecular meshwork on the ramp is elevated away from the outer wall of the Schlemm's canal without cutting the portion of the trabecular meshwork from surrounding portions of the trabecular meshwork and (ii) the portion is guided to first and second lateral elements separated by a gap and extending from a proximal side of the platform that is opposite the distal side of the platform, wherein the ramp increases from a distal thickness at the distal side to a proximal thickness, greater than the distal thickness, at the proximal side; and
creating first and second incisions through the trabecular meshwork with each of the first and second lateral elements while the portion of the trabecular meshwork remains elevated away from the outer wall of the Schlemm's canal so a strip of the trabecular meshwork has a width between the first and second incisions corresponding to a width of the gap.

10. The method of claim 9 , wherein creating the first and second incisions comprises creating only the first and second incisions.

11. The method of claim 9 , wherein the strip between the first and second incisions remains intact after creating the first and second incisions.

12. The method of claim 9 , further comprising excising the strip from the trabecular meshwork after the strip has reached a desired length.

13. The method of claim 9 , wherein creating the first and second incisions is performed without cautery or burning of the trabecular meshwork.

14. The method of claim 9 , wherein creating the first and second incisions is performed while the portion of the trabecular meshwork is stretched to be elevated away from the outer wall of the Schlemm's canal.

15. The method of claim 9 , wherein creating the first and second incisions is performed while the portion of the trabecular meshwork is under tension that is greater than the tension of the trabecular meshwork in a natural state.

16. The method of claim 9 , wherein the first lateral element creates the first incision along a first portion of the trabecular meshwork that is guided along a first side of the platform and the second lateral element creates the second incision along a second portion of the trabecular meshwork that is guided along a second side of the platform.

Assignees

• Univ Colorado Regents

Inventors

• Kahook Malik Y

Classifications

• A61B17/3209

  Incision instruments · CPC title

• A61F9/0133 Primary

  Knives or scalpels specially adapted therefor · CPC title

• A61F9/00736

  Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments (A61F9/008 takes precedence) · CPC title

• A61F9/00781

  Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment (drainage implants in general A61M27/002) · CPC title