Utility of nematode small molecules

US9868754B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9868754-B2
Application numberUS-201214237795-A
CountryUS
Kind codeB2
Filing dateAug 8, 2012
Priority dateAug 8, 2011
Publication dateJan 16, 2018
Grant dateJan 16, 2018

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method of alleviating or treating an inflammatory disorder in a human subject, comprising: administering to the subject a composition comprising isolated ascr#7 or a salt thereof; and wherein the inflammatory disorder is asthma, inflammatory bowel disease, or type one diabetes. 2. The method of claim 1 , wherein the method reduces mucus production in the subject. 3. The method of claim 1 , wherein the naturally occurring ascaroside is produced from a Nippostrongylus brasiliensis. 4. The method of claim 1 , wherein the inflammatory disorder is asthma. 5. The method of claim 1 , wherein the inflammatory disorder is inflammatory bowel disease. 6. The method of claim 1 , wherein the inflammatory disorder is type one diabetes.

Assignees

Inventors

Classifications

  • Immunomodulators · CPC title

  • Antianaemics · CPC title

  • Drugs for immunological or allergic disorders · CPC title

  • for hyperglycaemia, e.g. antidiabetics · CPC title

  • Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers · CPC title

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Frequently asked questions

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What does patent US9868754B2 cover?
The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture …
Who is the assignee on this patent?
Choe Andrea, Sternberg Paul W, Schroeder Frank C, and 3 more
What technology area does this patent fall under?
Primary CPC classification C07H15/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jan 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).