Quinazoline derivatives, compositions, and uses related thereto

US9868728B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9868728-B2
Application numberUS-201113876869-A
CountryUS
Kind codeB2
Filing dateOct 25, 2011
Priority dateOct 29, 2010
Publication dateJan 16, 2018
Grant dateJan 16, 2018

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The invention relates to quinazoline derivatives, compositions, and methods related thereto. In certain embodiments, the invention relates to inhibitors of NADPH-oxidase.

First claim

Opening claim text (preview).

The invention claimed is: 1. A pharmaceutical formulation comprising 6-chloro-3-(3-(dimethylamino)propyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one or salt thereof and a pharmaceutically acceptable carrier. 2. The pharmaceutical formulation of claim 1 in the form of a tablet, soft or hard gelatin or non-gelatin capsule, or caplet. 3. The pharmaceutical formulation of claim 1 wherein the pharmaceutically acceptable carrier is selected from dicalcium phosphate dihydrate, calcium sulfate, sucrose, glucose, dextrose, lactose, sorbitol, dextrose, cellulose, starch, gelatin, silicone dioxide, titanium oxide, magnesium aluminum silicate, magnesium stearate, calcium stearate, stearic acid, glycerol behenate, polyethylene glycol, talc, mineral oil, and an acrylic polymer. 4. The pharmaceutical formulation of claim 1 wherein the pharmaceutically acceptable carrier is a lubricant, surfactant, or enteric coating.

Assignees

Inventors

Classifications

  • for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia · CPC title

  • Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

  • Anti-Parkinson drugs · CPC title

  • Drugs for disorders of the respiratory system · CPC title

  • Antiasthmatics · CPC title

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Frequently asked questions

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What does patent US9868728B2 cover?
The invention relates to quinazoline derivatives, compositions, and methods related thereto. In certain embodiments, the invention relates to inhibitors of NADPH-oxidase.
Who is the assignee on this patent?
Lambeth John David, Ganesh Thota, Smith Susan M, and 2 more
What technology area does this patent fall under?
Primary CPC classification C07D417/12. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jan 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).