Scalable, massively parallel process for making micro-scale particles

Patent metadata

Field	Value
Publication number	US-9865887-B2
Application number	US-201514922907-A
Country	US
Kind code	B2
Filing date	Oct 26, 2015
Priority date	Oct 24, 2014
Publication date	Jan 9, 2018
Grant date	Jan 9, 2018

Abstract

A method of fabrication produces one or more functional microparticles using a parallel pore working piece. In one embodiment, the method forms a particle that includes a segment for the oxidation of a biofuel (such as glucose) and the reduction of oxygen. The particle may be synthesized in a structure with defined and parallel, uniform, thin pores that completely penetrate the structure. Further, the functional microparticle may be configured to reside in a human or animal body or cell such that i t may be self-contained fuel cell having an anode, a cathode, a separator membrane, and a magnetic component. In other embodiments, the functional microparticles may deliver energy or therapeutic materials in the body.

First claim

We claim:

1. A method for constructing at least one functional microparticle using a parallel pore working piece, the method comprising:
constructing the at least one functional microparticle in a structure with defined and parallel, uniform, thin pores that completely penetrate the structure,
wherein the functional microparticle has at least one dimension less than fifty microns in length, contains magnetizable material and emits electrical current, electromagnetic or thermal energy, or carries a therapeutic payload,
wherein the constructing further comprises electroplating a conductive initial layer into the pores of the parallel pore working piece and electrodepositing an anode onto the conductive initial layer prior to performing a vacuum-assisted filling, and
wherein the functional microparticle is generated by a combination of the electrodepositing, an etching of the working piece, and the vacuum-assisted filling, and results in the functional microparticle capable of energy conversion.

2. The method of claim 1 , wherein the constructing comprises performing the vacuum-assisted filling of a polymer, ceramic, or composite separator membrane into the pores of the parallel pore working piece, and onto the previously deposited anode.

3. The method of claim 2 , wherein the vacuum-assisted filling is performed by depositing a diluted polymer separator membrane material into the open pores of the parallel pore working piece.

4. The method of claim 2 , wherein the etching of the workpiece comprises widening the parallel pore working piece pores by etching the parallel pore working piece material, and the construction further comprises generating an insulating tube within the pores of the parallel pore working piece, and depositing a cathode after performing the vacuum-assisted filling.

5. The method of claim 4 , wherein the widening of the parallel pore working piece pores by etching includes using an aqueous solution of sodium hydroxide.

6. The method of claim 4 , wherein the insulating tube covers sidewalls of the pores.

7. The method of claim 1 , wherein the electroplating of the conductive initial layer is performed by electrodeposition implemented by exposing an open pore side of the membrane to an electrolyte and plating materials onto a side of a metal film at one end of the pores.

8. The method of claim 1 , wherein the constructing further comprises dispersing an oxygen-reducing agent in a separator membrane material that allows the passage of glucose but inhibits the passage of oxygen molecules.

9. A method for constructing at least one functional microparticle using a parallel pore working piece, the method comprising:
constructing the at least one functional microparticle in a structure with defined and parallel, uniform, thin pores that completely penetrate the structure,
wherein the functional microparticle has at least one dimension less than fifty microns in length, contains magnetizable material and emits electrical current, electromagnetic or thermal energy, or carries a therapeutic payload, and
further comprising preparing the parallel pore working piece for electroplating by applying a micron-thick metal film to one side of an anodized alumina filter membrane and placing the parallel pore working piece in water so as to wet the pores of the parallel pore working piece,
wherein the resulting particle contains components capable of converting energy.

10. The method of claim 9 , wherein the pore wetting process is performed by submerging the entire parallel pore working piece in water and applying sonication.

Assignees

• Weinberg Medical Physics Llc
• Weinberg Medical Physics Inc

Inventors

• Mair Lamar Odell
• Weinberg Irving N

Classifications

• H01M8/22

  Fuel cells in which the fuel is based on materials comprising carbon or oxygen or hydrogen and other elements; Fuel cells in which the fuel is based on materials comprising only elements other than carbon, oxygen or hydrogen · CPC title

• H01M2008/1095

  Fuel cells with polymeric electrolytes · CPC title

• Y02B90/18

  Cross-Sectional Technologies · mapped topic

• H01M4/8853

  Electrodeposition · CPC title

• A61K41/0052 Primary

  Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy · CPC title