Connectors for pneumatic devices in microfluidic systems

Patent metadata

Field	Value
Publication number	US-9861982-B2
Application number	US-201615006765-A
Country	US
Kind code	B2
Filing date	Jan 26, 2016
Priority date	Mar 9, 2015
Publication date	Jan 9, 2018
Grant date	Jan 9, 2018

Abstract

In one embodiment, a removable pneumatic connector, comprises a body having a plurality of bores passing through, each bore surrounded by a sealing member on an inner surface of the body. A plurality of gas lines may be placed within a corresponding bore. A vacuum port is disposed on the inner surface of the body, and an outer seal on the inner surface of the body surrounds the sealing members and the vacuum port. A vacuum line may be placed within the vacuum port, and configured to deliver negative pressure to the vacuum port. A vacuum holding area is created in the volume between the outer seal and each of the sealing members when the inner surface of the body is placed against a substrate. When the vacuum line is activated, a vacuum is created within the vacuum holding area, creating a positive seal between the body and the substrate.

First claim

What is claimed is:

1. A system for performing pneumatic control of a microfluidic device, comprising:
a pneumatic connector, the pneumatic connector comprising a housing having a tubing end, an engagement end and a plurality of channels passing through the housing, each channel further comprising a filter disposed between the tubing end and the engagement end; and
a pneumatic controller, the pneumatic controller comprising an interface;
wherein the plurality of channels are each in communication with the interface of the pneumatic controller on the engagement end, the pneumatic controller configured to supply variable pressure to each of said plurality of channels through said interface.

2. The system of claim 1 , wherein said filters comprise hydrophobic filters.

3. The system of claim 1 , wherein the pneumatic controller is configured to supply negative pressure to at least one of said plurality of channels.

4. The system of claim 1 , wherein each channel of the plurality of channels comprises a port configured to engage with a corresponding port on an interface of the pneumatic controller.

5. The system of claim 4 , wherein the port configured to engage with a corresponding port on an interface of the pneumatic controller comprises a male port configured to be received by a corresponding female port on an interface of the pneumatic controller.

6. The system of claim 5 , wherein the plurality of channels further comprises a plurality of bores, each male port of the plurality of ports placed within a corresponding bore.

7. The system of claim 5 , wherein the male port comprises a syringe.

8. The system of claim 7 , wherein the syringe comprises a tapered portion configured to be received by the filter such that the syringe is in fluid communication with the filter.

9. The system of claim 1 , wherein the pneumatic connector further comprises a magnet for magnetically securing the pneumatic connector to the controller.

10. The pneumatic connector of claim 1 , wherein the controller further comprises a magnet for magnetically securing the pneumatic connector to the controller.

Assignees

• Emd Millipore Corp

Inventors

• Gaige Terry
• Zayac Andrew
• Sydlowski Paul
• Lee Philip

Classifications

• C12M23/16 Primary

  Microfluidic devices; Capillary tubes (integrated microfluidic structures B01L3/5027; microreactors B01J19/0093) · CPC title

• B01L2400/049

  vacuum · CPC title

• B01L3/502715 Primary

  characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces · CPC title

• C12M23/40

  Manifolds; Distribution pieces (fluid transfer means B01L3/563) · CPC title

• B01L2300/14

  Means for pressure control · CPC title