Method for Cancer Therapy Based on Co-Administration of a Parvovirus and a Cytokine
US-2016367609-A1 · Dec 22, 2016 · US
Oncolytic virotherapy for prevention of tumor recurrence
US9861669B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9861669-B2 |
| Application number | US-201013376137-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 19, 2010 |
| Priority date | Jun 4, 2009 |
| Publication date | Jan 9, 2018 |
| Grant date | Jan 9, 2018 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Described is a parvovirus for preventing recurrence of a tumor, preferably a malignant brain tumor or pancreas tumor.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of reducing the rate of recurrence of tumors in a subject, comprising administering a parvovirus to the subject wherein the parvovirus is administered in a dose sufficient to prime the immune system against a tumor and thereby reduce the rate of recurrence of the tumor wherein the parvovirus is H1 (HIPV), wherein the tumor is a pancreas tumor and wherein the dose of parvovirus is about 1×10 9 plaque-forming units. 2. The method according to claim 1 , wherein said parvovirus is administered by intravenous (i.v.) or intratumoral administration. 3. The method of claim 1 , wherein priming of the immune system against the tumor is assayed by testing lymphocytes from the subject after treatment with the parvovirus for immune activity against the tumor cells.
Assignees
Inventors
Classifications
Antineoplastic agents · CPC title
Drugs for disorders of the nervous system · CPC title
for pancreatic disorders, e.g. pancreatic enzymes · CPC title
Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent · CPC title
- A61K35/768Primary
Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766 · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9861669B2 cover?
- Described is a parvovirus for preventing recurrence of a tumor, preferably a malignant brain tumor or pancreas tumor.
- Who is the assignee on this patent?
- Rommelaere Jean, Raykov Zahari, Grekova Svitlana, and 6 more
- What technology area does this patent fall under?
- Primary CPC classification A61K35/768. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jan 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).