Neprilysin inhibitors
US-9688692-B2 · Jun 27, 2017 · US
US9845332B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9845332-B2 |
| Application number | US-201715599769-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 19, 2017 |
| Priority date | Dec 15, 2010 |
| Publication date | Dec 19, 2017 |
| Grant date | Dec 19, 2017 |
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In one aspect, the invention relates to compounds having the formula: where R 1 -R 6 , a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
Opening claim text (preview).
What is claimed is: 1. (2R,4R)-5-Biphenyl-4-yl-2-hydroxy-4-[(1-hydroxy-1H-[1,2,3]triazole-4-carbonyl)-amino]-pentanoic acid or a pharmaceutically acceptable salt thereof.
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