Six-membered ring benzo derivatives as dpp-4 inhibitor and use thereof
US-2017313715-A1 · Nov 2, 2017 · US
US9840487B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9840487-B2 |
| Application number | US-201715487592-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 14, 2017 |
| Priority date | May 1, 2014 |
| Publication date | Dec 12, 2017 |
| Grant date | Dec 12, 2017 |
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Methods to access 2-aryl chromene compounds via an asymmetric catalytic process.
Opening claim text (preview).
We claim: 1. A composition comprising compounds of a formula wherein R is selected from H, halo, alkyl and alkoxy moieties and Ar is selected from phenyl and substituted phenyl moieties, said phenyl substituents selected from halo, alkyl, alkoxy, nitro and haloalkyl substituents, multiple said substituents and combinations thereof, said composition comprising at least about 70% an enantiomer of a formula 2. The composition of claim 1 wherein said phenyl moiety is selected from methyl, a methoxy, fluoro, chloro, nitro and dichloro substituted phenyl moieties, said composition comprising at least about 90% said enantiomer.
the oxygen atom being part of a five-membered ring · CPC title
2,3-Dihydro derivatives, e.g. flavanones · CPC title
with aryl radicals attached in position 2 · CPC title
Hydrogenated pyridine rings · CPC title
Asymmetric syntheses · CPC title
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